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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
| Target ID |
GM-T23934
|
| Target Name |
CCL23
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6368
|
| Gene ID |
6368 (Homo sapiens)
|
| Target Alternative Names |
C-C motif chemokine 23,CCL23,CK-BETA-8,CK-beta-8 (CKB-8),CKb8,Ckb-8,Ckb-8-1,MIP-3,MIP3,MPIF-1,Macrophage inflammatory protein 3 (MIP-3),Myeloid progenitor inhibitory factor 1 (MPIF-1),SCYA23,Small-inducible cytokine A23,hmrp-2a
|
| Uniprot Accession |
P55773
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSG00000274736
|
Pre-made viral vector of CCL23 cDNA Clones/ORF Plasmid
CCL23 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6368 | Pre-made Human CCL23/CKb8/MIP3 siRNA oligo Duplex | 6368 | Human | In-vitro grade; in-vivo grade | Detail |
CCL23 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23934-Ab | Human | Anti-Human CCL23 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CCL23 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23934-Ag | Human | Human CCL23 recombinant protein | Mammalian cell | Detail |