Explore CD14 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
| Target ID |
GM-T23212
|
| Target Name |
CD14
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
929
|
| Gene ID |
101096132 (Felis catus), 12475 (Mus musculus), 281048 (Bos taurus), 60350 (Rattus norvegicus)
607076 (Canis lupus familiaris), 697482 (Macaca mulatta), 929 (Homo sapiens)
|
| Target Alternative Names |
CD14,Cd14
|
| Uniprot Accession |
P10810,Q95122,Q63691,P08571
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer, Kidney transplant rejection, Congenital occlusion of ureteropelvic junction
|
| Disease from KEGG |
MAPK signaling pathway, NF-kappa B signaling pathway, Phagosome, Toll-like receptor signaling pathway, Hematopoietic cell lineage, Alcoholic liver disease, Pertussis, Legionellosis, Amoebiasis, Tuberculosis, Acute myeloid leukemia, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSMUSG00000051439, ENSBTAG00000015032, ENSCAFG00845001909, ENSMMUG00000010007, ENSG00000170458
|
| Target Classification |
|
Pre-made viral vector of CD14 cDNA Clones/ORF Plasmid
CD14 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo929 | Pre-made Human CD14 siRNA oligo Duplex | 929 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60350 | Pre-made Rat Cd14 siRNA oligo Duplex | 60350 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12475 | Pre-made Mouse Cd14 siRNA oligo Duplex | 12475 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697482 | Pre-made Cynomolgus/Rhesus macaque CD14 siRNA oligo Duplex | 697482 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096132 | Pre-made Cat/Feline CD14 siRNA oligo Duplex | 101096132 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607076 | Pre-made Dog/Canine CD14 siRNA oligo Duplex | 607076 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281048 | Pre-made Bovines/Cattle CD14 siRNA oligo Duplex | 281048 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
CD14 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23212-Ab | Human | Anti-Human CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T23212-Ab | Rat | Anti-Rat CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T23212-Ab | Mouse | Anti-Mouse CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T23212-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T23212-Ab | Cat/Feline | Anti-Cat/Feline CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T23212-Ab | Dog/Canine | Anti-Dog/Canine CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T23212-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD14 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23212-Ag | Human | Human CD14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T23212-Ag | Rat | Rat CD14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T23212-Ag | Mouse | Mouse CD14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T23212-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T23212-Ag | Cat/Feline | Cat/Feline CD14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T23212-Ag | Dog/Canine | Dog/Canine CD14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T23212-Ag | Bovines/Cattle | Bovines/Cattle CD14 VLP (virus-like particle) | HEK293 | Products Developing |
