Explore CEACAM3/CD66d gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]
| Target ID |
GM-T21890
|
| Target Name |
CEACAM3/CD66d
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1084
|
| Gene ID |
1084 (Homo sapiens), 707824 (Macaca mulatta)
|
| Target Alternative Names |
CEACAM3,CEA,CGM1,W264,W282,CD66D,CGM1a
|
| Uniprot Accession |
P40198
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Diagnostics Biomarker, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSG00000170956, ENSMMUG00000018103
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CEACAM3/CD66d cDNA Clones/ORF Plasmid
CEACAM3/CD66d siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1084 | Pre-made Human CEACAM3/CEA/CGM1 siRNA oligo Duplex | 1084 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707824 | Pre-made Cynomolgus/Rhesus macaque CEACAM3 siRNA oligo Duplex | 707824 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
CEACAM3/CD66d antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T21890-Ab | Human | Anti-Human CEACAM3/CD66d monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T21890-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CEACAM3/CD66d monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
CEACAM3/CD66d VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T21890-Ag | Human | Human CEACAM3/CD66d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T21890-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CEACAM3/CD66d VLP (virus-like particle) | HEK293 | Products Developing |
