Explore MTR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
| Target ID |
GM-T21661
|
| Target Name |
MTR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4548
|
| Gene ID |
100050270 (Equus caballus), 101101166 (Felis catus), 238505 (Mus musculus), 280869 (Bos taurus)
4548 (Homo sapiens), 479190 (Canis lupus familiaris), 717582 (Macaca mulatta), 81522 (Rattus norvegicus)
|
| Target Alternative Names |
MTR,Mtr,MS,D830038K18Rik,HMAG,cblG,methioninesynthase
|
| Uniprot Accession |
A6H5Y3,Q4JIJ3,Q99707,Q9Z2Q4
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000021661, ENSMUSG00000021311, ENSBTAG00000012251, ENSG00000116984, ENSCAFG00845002493, ENSMMUG00000010073
|
| Target Classification |
|
MTR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4548 | Pre-made Human MTR/MS/HMAG siRNA oligo Duplex | 4548 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81522 | Pre-made Rat Mtr/methioninesynthase siRNA oligo Duplex | 81522 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo238505 | Pre-made Mouse Mtr/MS/D830038K18Rik siRNA oligo Duplex | 238505 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717582 | Pre-made Cynomolgus/Rhesus macaque MTR siRNA oligo Duplex | 717582 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101166 | Pre-made Cat/Feline MTR siRNA oligo Duplex | 101101166 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479190 | Pre-made Dog/Canine MTR siRNA oligo Duplex | 479190 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280869 | Pre-made Bovines/Cattle MTR siRNA oligo Duplex | 280869 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050270 | Pre-made Equine/Horse MTR siRNA oligo Duplex | 100050270 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MTR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T21661-Ab | Human | Anti-Human MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T21661-Ab | Rat | Anti-Rat MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T21661-Ab | Mouse | Anti-Mouse MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T21661-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T21661-Ab | Cat/Feline | Anti-Cat/Feline MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T21661-Ab | Dog/Canine | Anti-Dog/Canine MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T21661-Ab | Bovines/Cattle | Anti-Bovines/Cattle MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T21661-Ab | Equine/Horse | Anti-Equine/Horse MTR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MTR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T21661-Ag | Human | Human MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T21661-Ag | Rat | Rat MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T21661-Ag | Mouse | Mouse MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T21661-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T21661-Ag | Cat/Feline | Cat/Feline MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T21661-Ag | Dog/Canine | Dog/Canine MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T21661-Ag | Bovines/Cattle | Bovines/Cattle MTR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T21661-Ag | Equine/Horse | Equine/Horse MTR recombinant protein | Mammalian cell | Detail |
