Recombinant multi-species MTR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MTR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
The Alternative Names of target: MTR,Methionine synthase,MS,5-methyltetrahydrofolate--homocysteine methyltransferase, Cobalamin-dependent methionine synthase, Vitamin-B12 dependent methionine synthase,MS,HMAG,cblG

Target products collectionGo to MTR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T21661-Ab-1/ GM-Tg-hg-T21661-Ab-2 Human MTR protein Human
GM-Tg-rg-T21661-Ab-1/ GM-Tg-rg-T21661-Ab-2 Rat MTR protein Rat
GM-Tg-mg-T21661-Ab-1/ GM-Tg-mg-T21661-Ab-2 Mouse MTR protein Mouse
GM-Tg-cynog-T21661-Ab-1/ GM-Tg-cynog-T21661-Ab-2 Cynomolgus/Rhesus macaque MTR monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T21661-Ab-1/ GM-Tg-felg-T21661-Ab-2 Feline MTR protein Feline
GM-Tg-cang-T21661-Ab-1/ GM-Tg-cang-T21661-Ab-2 Canine MTR protein Canine
GM-Tg-bovg-T21661-Ab-1/ GM-Tg-bovg-T21661-Ab-2 Bovine MTR protein Bovine
GM-Tg-equg-T21661-Ab-1/ GM-Tg-equg-T21661-Ab-2 Equine MTR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T21661-Ab-1/ GM-Tg-hg-T21661-Ab-2; GM-Tg-rg-T21661-Ab-1/ GM-Tg-rg-T21661-Ab-2;
GM-Tg-mg-T21661-Ab-1/ GM-Tg-mg-T21661-Ab-2; GM-Tg-cynog-T21661-Ab-1/ GM-Tg-cynog-T21661-Ab-2;
GM-Tg-felg-T21661-Ab-1/ GM-Tg-felg-T21661-Ab-2; GM-Tg-cang-T21661-Ab-1/ GM-Tg-cang-T21661-Ab-2;
GM-Tg-bovg-T21661-Ab-1/ GM-Tg-bovg-T21661-Ab-2; GM-Tg-equg-T21661-Ab-1/ GM-Tg-equg-T21661-Ab-2
Products Name MTR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MTR
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MTR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.