Explore HIF2α/EPAS1/HIF-2A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
| Target ID |
GM-T21123
|
| Target Name |
HIF2α/EPAS1/HIF-2A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2034
|
| Gene ID |
100068622 (Equus caballus), 101085621 (Felis catus), 13819 (Mus musculus), 2034 (Homo sapiens)
282711 (Bos taurus), 29452 (Rattus norvegicus), 474578 (Canis lupus familiaris), 714641 (Macaca mulatta)
|
| Target Alternative Names |
Basic-helix-loop-helix-PAS protein MOP2,Class E basic helix-loop-helix protein 73 (bHLHe73),ECYT4,EPAS-1,EPAS1,Endothelial PAS domain-containing protein 1,Epas1,HIF-1-alpha-like factor (HLF),HIF-2 alpha,HIF-2A,HIF-2alpha,HIF2 alpha,HIF2-alpha),HIF2A,HIF2α,HLF,HRF,Hif2a,Hypoxia-inducible factor 2-alpha (HIF-2-alpha,MOP2,Member of PAS protein 2,PAS domain-containing protein 2,PASD2,bHLHe73
|
| Uniprot Accession |
P97481,Q99814,Q9JHS1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Pathways in cancer, Renal cell carcinoma
|
| Gene Ensembl |
ENSECAG00000014594, ENSMUSG00000024140, ENSG00000116016, ENSBTAG00000003711, ENSCAFG00845027702, ENSMMUG00000023326
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of HIF2α/EPAS1/HIF-2A cDNA Clones/ORF Plasmid
HIF2α/EPAS1/HIF-2A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2034 | Pre-made Human EPAS1/HLF/MOP2 siRNA oligo Duplex | 2034 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29452 | Pre-made Rat Epas1/HLF/Hif2a siRNA oligo Duplex | 29452 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13819 | Pre-made Mouse Epas1/HLF/HRF siRNA oligo Duplex | 13819 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714641 | Pre-made Cynomolgus/Rhesus macaque EPAS1 siRNA oligo Duplex | 714641 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085621 | Pre-made Cat/Feline EPAS1 siRNA oligo Duplex | 101085621 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474578 | Pre-made Dog/Canine EPAS1 siRNA oligo Duplex | 474578 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282711 | Pre-made Bovines/Cattle EPAS1 siRNA oligo Duplex | 282711 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068622 | Pre-made Equine/Horse EPAS1 siRNA oligo Duplex | 100068622 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HIF2α/EPAS1/HIF-2A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T21123-Ab | Human | Anti-Human HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T21123-Ab | Rat | Anti-Rat HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T21123-Ab | Mouse | Anti-Mouse HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T21123-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T21123-Ab | Cat/Feline | Anti-Cat/Feline HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T21123-Ab | Dog/Canine | Anti-Dog/Canine HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T21123-Ab | Bovines/Cattle | Anti-Bovines/Cattle HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T21123-Ab | Equine/Horse | Anti-Equine/Horse HIF2α/EPAS1/HIF-2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HIF2α/EPAS1/HIF-2A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T21123-Ag | Human | Human HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T21123-Ag | Rat | Rat HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T21123-Ag | Mouse | Mouse HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T21123-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T21123-Ag | Cat/Feline | Cat/Feline HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T21123-Ag | Dog/Canine | Dog/Canine HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T21123-Ag | Bovines/Cattle | Bovines/Cattle HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T21123-Ag | Equine/Horse | Equine/Horse HIF2α/EPAS1/HIF-2A recombinant protein | Mammalian cell | Detail |
