AVP Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore AVP gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20.

Target ID GM-T20975
Target Name AVP
Gene Group ldentifer
(Target Gene ID in Homo species)
551
Gene ID 100066842 (Equus caballus), 101096305 (Felis catus), 11998 (Mus musculus), 24221 (Rattus norvegicus)
280728 (Bos taurus), 403579 (Canis lupus familiaris), 551 (Homo sapiens), 717101 (Macaca mulatta)
Target Alternative Names ADH,ARVP,AVP,AVP-NPII,AVRP,Avp,DI,VP,Vas,Vasopressin-neurophysin 2-copeptin,Vp,Vsp
Uniprot Accession P01182,P35455,P01186,P01180,P01185
Protein Sub-location Secreted Protein/Potential Cytokines
Category Therapeutics Target
Disease from KEGG Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
Gene Ensembl ENSMUSG00000037727, ENSBTAG00000008027, ENSCAFG00845015347, ENSG00000101200, ENSMMUG00000051923


Pre-made viral vector of AVP cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002893Human AVP/ADH/ARVP Lentivirus plasmidNM_000490551HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002893Human AVP/ADH/ARVP Lentivirus particleNM_000490551HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm001228Mouse Avp/Vp/Vsp Lentivirus plasmidNM_00973211998MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm001228Mouse Avp/Vp/Vsp Lentivirus particleNM_00973211998MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


AVP siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo551Pre-made Human AVP/VP/ADH siRNA oligo Duplex551HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo24221Pre-made Rat Avp/DI/VP siRNA oligo Duplex24221RatIn-vitro grade; in-vivo gradeDetail
pGMoligo11998Pre-made Mouse Avp/Vp/Vsp siRNA oligo Duplex11998MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo717101Pre-made Cynomolgus/Rhesus macaque AVP siRNA oligo Duplex717101Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101096305Pre-made Cat/Feline AVP siRNA oligo Duplex101096305Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403579Pre-made Dog/Canine AVP siRNA oligo Duplex403579Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo280728Pre-made Bovines/Cattle AVP/AVP-NPII siRNA oligo Duplex280728Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100066842Pre-made Equine/Horse AVP siRNA oligo Duplex100066842Equine/HorseIn-vitro grade; in-vivo gradeDetail


AVP antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T20975-AbHumanAnti-Human AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T20975-AbRatAnti-Rat AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T20975-AbMouseAnti-Mouse AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T20975-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T20975-AbCat/FelineAnti-Cat/Feline AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T20975-AbDog/CanineAnti-Dog/Canine AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T20975-AbBovines/CattleAnti-Bovines/Cattle AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T20975-AbEquine/HorseAnti-Equine/Horse AVP monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


AVP recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T20975-AgHumanHuman AVP recombinant proteinMammalian cellDetail
GM-Tg-rg-T20975-AgRatRat AVP recombinant proteinMammalian cellDetail
GM-Tg-mg-T20975-AgMouseMouse AVP recombinant proteinMammalian cellDetail
GM-Tg-cynog-T20975-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque AVP recombinant proteinMammalian cellDetail
GM-Tg-felg-T20975-AgCat/FelineCat/Feline AVP recombinant proteinMammalian cellDetail
GM-Tg-cang-T20975-AgDog/CanineDog/Canine AVP recombinant proteinMammalian cellDetail
GM-Tg-bovg-T20975-AgBovines/CattleBovines/Cattle AVP recombinant proteinMammalian cellDetail
GM-Tg-equg-T20975-AgEquine/HorseEquine/Horse AVP recombinant proteinMammalian cellDetail