Explore Adrenomedullin/ADM gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014]
| Target ID |
GM-T20629
|
| Target Name |
Adrenomedullin/ADM
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
133
|
| Gene ID |
100033857 (Equus caballus), 101087095 (Felis catus), 11535 (Mus musculus), 133 (Homo sapiens)
25026 (Rattus norvegicus), 280713 (Bos taurus), 403817 (Canis lupus familiaris), 703305 (Macaca mulatta)
|
| Target Alternative Names |
ADM,AM,AMPP,Adm,Adrenomedullin,Ap,H39316,PAMP,Pro-adrenomedullin,RATAP
|
| Uniprot Accession |
P97297,P35318,P43145,O62827,O77559
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
Acute tubulo-interstitial nephritis, lung cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
|
| Gene Ensembl |
ENSMUSG00000030790, ENSG00000148926, ENSBTAG00000021048, ENSCAFG00845014478, ENSMMUG00000016387
|
Pre-made viral vector of Adrenomedullin/ADM cDNA Clones/ORF Plasmid
Adrenomedullin/ADM siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo133 | Pre-made Human ADM/AM/PAMP siRNA oligo Duplex | 133 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25026 | Pre-made Rat Adm/Ap/RATAP siRNA oligo Duplex | 25026 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11535 | Pre-made Mouse Adm/AM siRNA oligo Duplex | 11535 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703305 | Pre-made Cynomolgus/Rhesus macaque ADM siRNA oligo Duplex | 703305 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087095 | Pre-made Cat/Feline ADM siRNA oligo Duplex | 101087095 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403817 | Pre-made Dog/Canine ADM siRNA oligo Duplex | 403817 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280713 | Pre-made Bovines/Cattle ADM siRNA oligo Duplex | 280713 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033857 | Pre-made Equine/Horse ADM/AMPP siRNA oligo Duplex | 100033857 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Adrenomedullin/ADM antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T20629-Ab | Human | Anti-Human Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T20629-Ab | Rat | Anti-Rat Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T20629-Ab | Mouse | Anti-Mouse Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T20629-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T20629-Ab | Cat/Feline | Anti-Cat/Feline Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T20629-Ab | Dog/Canine | Anti-Dog/Canine Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T20629-Ab | Bovines/Cattle | Anti-Bovines/Cattle Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T20629-Ab | Equine/Horse | Anti-Equine/Horse Adrenomedullin/ADM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Adrenomedullin/ADM recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T20629-Ag | Human | Human Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T20629-Ag | Rat | Rat Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T20629-Ag | Mouse | Mouse Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T20629-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T20629-Ag | Cat/Feline | Cat/Feline Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T20629-Ag | Dog/Canine | Dog/Canine Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T20629-Ag | Bovines/Cattle | Bovines/Cattle Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T20629-Ag | Equine/Horse | Equine/Horse Adrenomedullin/ADM recombinant protein | Mammalian cell | Detail |
