Explore FGF7 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T19852
|
| Target Name |
FGF7
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2252
|
| Gene ID |
100033961 (Equus caballus), 101097982 (Felis catus), 14178 (Mus musculus), 2252 (Homo sapiens)
29348 (Rattus norvegicus), 403915 (Canis lupus familiaris), 574345 (Macaca mulatta), 616885 (Bos taurus)
|
| Target Alternative Names |
FGF-7,FGF5B,FGF7,Fgf5b,Fgf7,Fibroblast growth factor 7,HBGF-7,Heparin-binding growth factor 7 (HBGF-7),KGF,KGF/FGF7,Keratinocyte growth factor,Kgf
|
| Uniprot Accession |
P36363,P21781,Q02195,P79150
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer, Acute respiratory distress syndrome (ARDS)
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Chemical carcinogenesis - receptor activation, Melanoma, Breast cancer, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000015510, ENSMUSG00000027208, ENSG00000140285, ENSCAFG00845022021, ENSMMUG00000009842, ENSBTAG00000051898
|
Pre-made viral vector of FGF7 cDNA Clones/ORF Plasmid
FGF7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2252 | Pre-made Human FGF7/KGF/HBGF-7 siRNA oligo Duplex | 2252 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29348 | Pre-made Rat Fgf7/Kgf/Fgf5b siRNA oligo Duplex | 29348 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14178 | Pre-made Mouse Fgf7/Kgf/Fgf5b siRNA oligo Duplex | 14178 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574345 | Pre-made Cynomolgus/Rhesus macaque FGF7/KGF siRNA oligo Duplex | 574345 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097982 | Pre-made Cat/Feline FGF7 siRNA oligo Duplex | 101097982 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403915 | Pre-made Dog/Canine FGF7/KGF siRNA oligo Duplex | 403915 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo616885 | Pre-made Bovines/Cattle FGF7/FGF5B siRNA oligo Duplex | 616885 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033961 | Pre-made Equine/Horse FGF7/FGF5B siRNA oligo Duplex | 100033961 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FGF7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T19852-Ab | Human | Anti-Human FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T19852-Ab | Rat | Anti-Rat FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T19852-Ab | Mouse | Anti-Mouse FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T19852-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T19852-Ab | Cat/Feline | Anti-Cat/Feline FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T19852-Ab | Dog/Canine | Anti-Dog/Canine FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T19852-Ab | Bovines/Cattle | Anti-Bovines/Cattle FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T19852-Ab | Equine/Horse | Anti-Equine/Horse FGF7 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
FGF7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T19852-Ag | Human | Human FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T19852-Ag | Rat | Rat FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T19852-Ag | Mouse | Mouse FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T19852-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T19852-Ag | Cat/Feline | Cat/Feline FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T19852-Ag | Dog/Canine | Dog/Canine FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T19852-Ag | Bovines/Cattle | Bovines/Cattle FGF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T19852-Ag | Equine/Horse | Equine/Horse FGF7 recombinant protein | Mammalian cell | Detail |
