Explore GNRH1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T18950
|
| Target Name |
GNRH1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2796
|
| Gene ID |
100630270 (Equus caballus), 101080783 (Felis catus), 14714 (Mus musculus), 25194 (Rattus norvegicus)
2796 (Homo sapiens), 608671 (Canis lupus familiaris), 613033 (Macaca mulatta), 768325 (Bos taurus)
|
| Target Alternative Names |
GNRH,GNRH1,GRH,Gnrh,Gnrh1,Gnrh2,Gnrha,LHRH,LNRH,Lhrh,Lhrh1,Lnrh,Progonadoliberin I,Progonadoliberin-1,Rgnrhg1,SH-4,hpg
|
| Uniprot Accession |
P13562,P07490,P55248,P01148,P55247
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, GnRH signaling pathway, GnRH secretion
|
| Gene Ensembl |
ENSMUSG00000015812, ENSG00000147437, ENSCAFG00845014221, ENSMMUG00000029018, ENSBTAG00000000164
|
Pre-made viral vector of GNRH1 cDNA Clones/ORF Plasmid
GNRH1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2796 | Pre-made Human GNRH1/GRH/GNRH siRNA oligo Duplex | 2796 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25194 | Pre-made Rat Gnrh1/Gnrh/Lhrh siRNA oligo Duplex | 25194 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14714 | Pre-made Mouse Gnrh1/hpg/Gnrh siRNA oligo Duplex | 14714 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613033 | Pre-made Cynomolgus/Rhesus macaque GNRH1/GNRH/LHRH siRNA oligo Duplex | 613033 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080783 | Pre-made Cat/Feline GNRH1 siRNA oligo Duplex | 101080783 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608671 | Pre-made Dog/Canine GNRH1 siRNA oligo Duplex | 608671 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo768325 | Pre-made Bovines/Cattle GNRH1 siRNA oligo Duplex | 768325 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100630270 | Pre-made Equine/Horse GNRH1 siRNA oligo Duplex | 100630270 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GNRH1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T18950-Ab | Human | Anti-Human GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T18950-Ab | Rat | Anti-Rat GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T18950-Ab | Mouse | Anti-Mouse GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T18950-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T18950-Ab | Cat/Feline | Anti-Cat/Feline GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T18950-Ab | Dog/Canine | Anti-Dog/Canine GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T18950-Ab | Bovines/Cattle | Anti-Bovines/Cattle GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T18950-Ab | Equine/Horse | Anti-Equine/Horse GNRH1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GNRH1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T18950-Ag | Human | Human GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T18950-Ag | Rat | Rat GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T18950-Ag | Mouse | Mouse GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T18950-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T18950-Ag | Cat/Feline | Cat/Feline GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T18950-Ag | Dog/Canine | Dog/Canine GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T18950-Ag | Bovines/Cattle | Bovines/Cattle GNRH1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T18950-Ag | Equine/Horse | Equine/Horse GNRH1 recombinant protein | Mammalian cell | Detail |
