Explore HTRA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T17642
|
| Target Name |
HTRA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5654
|
| Gene ID |
100064570 (Equus caballus), 101095920 (Felis catus), 282326 (Bos taurus), 477852 (Canis lupus familiaris)
56213 (Mus musculus), 5654 (Homo sapiens), 65164 (Rattus norvegicus), 705855 (Macaca mulatta)
|
| Target Alternative Names |
ARMD7,CADASIL2,CARASIL,HTRA,HTRA1,High-temperature requirement A serine peptidase 1,HtrA,Htra1,L56,ORF480,PRSS11,Prss11,RSPP11,Serine protease 11,Serine protease HTRA1
|
| Uniprot Accession |
F1N152,Q9R118,Q92743,Q9QZK5
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer, Ovary Cancer, small vessel disease (SVD)
|
| Gene Ensembl |
ENSECAG00000009990, ENSBTAG00000008389, ENSMUSG00000006205, ENSG00000166033, ENSMMUG00000056637
|
Pre-made viral vector of HTRA1 cDNA Clones/ORF Plasmid
HTRA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5654 | Pre-made Human HTRA1/L56/HtrA siRNA oligo Duplex | 5654 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65164 | Pre-made Rat Htra1/Prss11 siRNA oligo Duplex | 65164 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56213 | Pre-made Mouse Htra1/L56/HTRA siRNA oligo Duplex | 56213 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo705855 | Pre-made Cynomolgus/Rhesus macaque HTRA1 siRNA oligo Duplex | 705855 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095920 | Pre-made Cat/Feline HTRA1 siRNA oligo Duplex | 101095920 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477852 | Pre-made Dog/Canine HTRA1/PRSS11 siRNA oligo Duplex | 477852 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282326 | Pre-made Bovines/Cattle HTRA1/PRSS11 siRNA oligo Duplex | 282326 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064570 | Pre-made Equine/Horse HTRA1 siRNA oligo Duplex | 100064570 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HTRA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T17642-Ab | Human | Anti-Human HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T17642-Ab | Rat | Anti-Rat HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T17642-Ab | Mouse | Anti-Mouse HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T17642-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T17642-Ab | Cat/Feline | Anti-Cat/Feline HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T17642-Ab | Dog/Canine | Anti-Dog/Canine HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T17642-Ab | Bovines/Cattle | Anti-Bovines/Cattle HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T17642-Ab | Equine/Horse | Anti-Equine/Horse HTRA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HTRA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T17642-Ag | Human | Human HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T17642-Ag | Rat | Rat HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T17642-Ag | Mouse | Mouse HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T17642-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T17642-Ag | Cat/Feline | Cat/Feline HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T17642-Ag | Dog/Canine | Dog/Canine HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T17642-Ag | Bovines/Cattle | Bovines/Cattle HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T17642-Ag | Equine/Horse | Equine/Horse HTRA1 VLP (virus-like particle) | HEK293 | Products Developing |
