Human HTRA1/ARMD7/CADASIL2 ORF/cDNA clone-Adenovirus particle (NM_002775)

Cat. No.: vGMAD000147

Pre-made Human HTRA1/ARMD7/CADASIL2 Adenovirus for HTRA1 overexpression in-vitro and in-vivo. The HTRA1 adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified HTRA1-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAD000147 Human HTRA1 Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAD000147
Gene Name HTRA1
Accession Number NM_002775
Gene ID 5654
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length 1443 bp
Gene Alias ARMD7,CADASIL2,CARASIL,HtrA,L56,ORF480,PRSS11
Fluorescent Reporter Null
Mammalian Cell Selection Null
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCAGATCCCGCGCGCCGCTCTTCTCCCGCTGCTGCTGCTGCTGCTGGCGGCGCCCGCCTCGGCGCAGCTGTCCCGGGCCGGCCGCTCGGCGCCTTTGGCCGCCGGGTGCCCAGACCGCTGCGAGCCGGCGCGCTGCCCGCCGCAGCCGGAGCACTGCGAGGGCGGCCGGGCCCGGGACGCGTGCGGCTGCTGCGAGGTGTGCGGCGCGCCCGAGGGCGCCGCGTGCGGCCTGCAGGAGGGCCCGTGCGGCGAGGGGCTGCAGTGCGTGGTGCCCTTCGGGGTGCCAGCCTCGGCCACGGTGCGGCGGCGCGCGCAGGCCGGCCTCTGTGTGTGCGCCAGCAGCGAGCCGGTGTGCGGCAGCGACGCCAACACCTACGCCAACCTGTGCCAGCTGCGCGCCGCCAGCCGCCGCTCCGAGAGGCTGCACCGGCCGCCGGTCATCGTCCTGCAGCGCGGAGCCTGCGGCCAAGGGCAGGAAGATCCCAACAGTTTGCGCCATAAATATAACTTTATCGCGGACGTGGTGGAGAAGATCGCCCCTGCCGTGGTTCATATCGAATTGTTTCGCAAGCTTCCGTTTTCTAAACGAGAGGTGCCGGTGGCTAGTGGGTCTGGGTTTATTGTGTCGGAAGATGGACTGATCGTGACAAATGCCCACGTGGTGACCAACAAGCACCGGGTCAAAGTTGAGCTGAAGAACGGTGCCACTTACGAAGCCAAAATCAAGGATGTGGATGAGAAAGCAGACATCGCACTCATCAAAATTGACCACCAGGGCAAGCTGCCTGTCCTGCTGCTTGGCCGCTCCTCAGAGCTGCGGCCGGGAGAGTTCGTGGTCGCCATCGGAAGCCCGTTTTCCCTTCAAAACACAGTCACCACCGGGATCGTGAGCACCACCCAGCGAGGCGGCAAAGAGCTGGGGCTCCGCAACTCAGACATGGACTACATCCAGACCGACGCCATCATCAACTATGGAAACTCGGGAGGCCCGTTAGTAAACCTGGACGGTGAAGTGATTGGAATTAACACTTTGAAAGTGACAGCTGGAATCTCCTTTGCAATCCCATCTGATAAGATTAAAAAGTTCCTCACGGAGTCCCATGACCGACAGGCCAAAGGAAAAGCCATCACCAAGAAGAAGTATATTGGTATCCGAATGATGTCACTCACGTCCAGCAAAGCCAAAGAGCTGAAGGACCGGCACCGGGACTTCCCAGACGTGATCTCAGGAGCGTATATAATTGAAGTAATTCCTGATACCCCAGCAGAAGCTGGTGGTCTCAAGGAAAACGACGTCATAATCAGCATCAATGGACAGTCCGTGGTCTCCGCCAATGATGTCAGCGACGTCATTAAAAGGGAAAGCACCCTGAACATGGTGGTCCGCAGGGGTAATGAAGATATCATGATCACAGTGATTCCCGAAGAAATTGACCCATAG
ORF Protein Sequence MQIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARDACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGSDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEIDP

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-668 Pre-Made Galegenimab biosimilar, Whole mAb, Anti-HTRA1 Antibody: Anti-ARMD7/CADASIL2/CARASIL/HtrA/L56/ORF480/PRSS11 therapeutic antibody
    Target Antibody GM-Tg-g-T17642-Ab Anti-HTRA1/ ARMD7/ CADASIL2 monoclonal antibody
    Target Antigen GM-Tg-g-T17642-Ag HTRA1 VLP (virus-like particle)
    ORF Viral Vector pGMLV001033 Human HTRA1 Lentivirus plasmid
    ORF Viral Vector pGMAD000147 Human HTRA1 Adenovirus plasmid
    ORF Viral Vector pGMPC000585 Human HTRA1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLV001033 Human HTRA1 Lentivirus particle
    ORF Viral Vector vGMAD000147 Human HTRA1 Adenovirus particle


    Target information

    Target ID GM-T17642
    Target Name HTRA1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		5654
    Gene ID 100064570 (Equus caballus), 101095920 (Felis catus), 282326 (Bos taurus), 477852 (Canis lupus familiaris)
    56213 (Mus musculus), 5654 (Homo sapiens), 65164 (Rattus norvegicus), 705855 (Macaca mulatta)
    Gene Symbols & Synonyms HTRA1,Htra1,PRSS11,L56,HTRA,Prss11,RSPP11,HtrA,ARMD7,ORF480,CARASIL,CADASIL2
    Target Alternative Names ARMD7,CADASIL2,CARASIL,HTRA,HTRA1,High-temperature requirement A serine peptidase 1,HtrA,Htra1,L56,ORF480,PRSS11,Prss11,RSPP11,Serine protease 11,Serine protease HTRA1
    Uniprot Accession F1N152,Q92743,Q9QZK5,Q9R118
    Additional SwissProt Accessions: F1N152,Q9R118,Q92743,Q9QZK5
    Uniprot Entry Name
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, INN Index
    Disease cancer, Ovary Cancer, small vessel disease (SVD)
    Disease from KEGG
    Gene Ensembl ENSECAG00000009990, ENSBTAG00000008389, ENSMUSG00000006205, ENSG00000166033, ENSMMUG00000056637
    Target Classification


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.