LEPR/Leptin R/CD295 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore LEPR/Leptin R/CD295 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]

Pre-made viral vector of LEPR/Leptin R/CD295 cDNA Clones/ORF Plasmid

LEPR/Leptin R/CD295 siRNA/miRNA/oligo for RNA interfence (RNAi)

LEPR/Leptin R/CD295 antibody/GMab

LEPR/Leptin R/CD295 recombinant protein