Explore C5aR/C5AR1/CD88 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Enables G protein-coupled receptor activity and complement component C5a receptor activity. Involved in several processes, including complement component C5a signaling pathway; mRNA transcription by RNA polymerase II; and positive regulation of ERK1 and ERK2 cascade. Located in apical part of cell and basolateral plasma membrane. Biomarker of Alzheimer's disease; asthma; chronic obstructive pulmonary disease; rhinitis; and severe acute respiratory syndrome. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T15439
|
| Target Name |
C5aR/C5AR1/CD88
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
728
|
| Gene ID |
100065997 (Equus caballus), 101098593 (Felis catus), 113959 (Rattus norvegicus), 12273 (Mus musculus)
442974 (Canis lupus familiaris), 493645 (Bos taurus), 718056 (Macaca mulatta), 728 (Homo sapiens)
|
| Target Alternative Names |
C5A,C5AR,C5AR1,C5R1,C5a anaphylatoxin chemotactic receptor (C5a-R,C5a anaphylatoxin chemotactic receptor 1,C5a-R,C5aR,C5aR),C5ar1,C5r1,CD88,Cd88,D7Msu1
|
| Uniprot Accession |
P97520,P30993,P30992,P79188,P21730
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Alcoholic liver disease, Staphylococcus aureus infection
|
| Gene Ensembl |
ENSECAG00000006153, ENSMUSG00000049130, ENSCAFG00845002761, ENSMMUG00000009278, ENSG00000197405
|
| Target Classification |
GPCR, Checkpoint-Immuno Oncology
|
Pre-made viral vector of C5aR/C5AR1/CD88 cDNA Clones/ORF Plasmid
C5aR/C5AR1/CD88 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo728 | Pre-made Human C5AR1/C5A/C5AR siRNA oligo Duplex | 728 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo113959 | Pre-made Rat C5ar1/C5aR/C5r1 siRNA oligo Duplex | 113959 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12273 | Pre-made Mouse C5ar1/C5aR/C5r1 siRNA oligo Duplex | 12273 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718056 | Pre-made Cynomolgus/Rhesus macaque C5AR1/C5AR/C5R1 siRNA oligo Duplex | 718056 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098593 | Pre-made Cat/Feline C5AR1 siRNA oligo Duplex | 101098593 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442974 | Pre-made Dog/Canine C5AR1/C5R1 siRNA oligo Duplex | 442974 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493645 | Pre-made Bovines/Cattle C5AR1/C5R1 siRNA oligo Duplex | 493645 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065997 | Pre-made Equine/Horse C5AR1 siRNA oligo Duplex | 100065997 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
C5aR/C5AR1/CD88 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15439-Ab | Human | Anti-Human C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T15439-Ab | Rat | Anti-Rat C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T15439-Ab | Mouse | Anti-Mouse C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T15439-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T15439-Ab | Cat/Feline | Anti-Cat/Feline C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T15439-Ab | Dog/Canine | Anti-Dog/Canine C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T15439-Ab | Bovines/Cattle | Anti-Bovines/Cattle C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T15439-Ab | Equine/Horse | Anti-Equine/Horse C5aR/C5AR1/CD88 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
C5aR/C5AR1/CD88 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15439-Ag | Human | Human C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T15439-Ag | Rat | Rat C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T15439-Ag | Mouse | Mouse C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T15439-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T15439-Ag | Cat/Feline | Cat/Feline C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T15439-Ag | Dog/Canine | Dog/Canine C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T15439-Ag | Bovines/Cattle | Bovines/Cattle C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T15439-Ag | Equine/Horse | Equine/Horse C5aR/C5AR1/CD88 VLP (virus-like particle) | HEK293 | Products Developing |
