Explore TNFRSF18/CD357 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
| Target ID |
GM-T15344
|
| Target Name |
TNFRSF18/CD357
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8784
|
| Gene ID |
100066195 (Equus caballus), 101083251 (Felis catus), 21936 (Mus musculus), 500598 (Rattus norvegicus)
516256 (Bos taurus), 606971 (Canis lupus familiaris), 699559 (Macaca mulatta), 8784 (Homo sapiens)
|
| Target Alternative Names |
AITR,Activation-inducible TNFR family receptor,CD357,ENERGEN,GITR,GITR-D,Gitr,Glucocorticoid-induced TNFR-related protein,TNFRSF18,Tnfrsf18,Tumor necrosis factor receptor superfamily member 18
|
| Uniprot Accession |
O35714,Q9Y5U5
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSMUSG00000041954, ENSBTAG00000015632, ENSCAFG00845022900, ENSMMUG00000014205, ENSG00000186891
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of TNFRSF18/CD357 cDNA Clones/ORF Plasmid
TNFRSF18/CD357 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8784 | Pre-made Human TNFRSF18/AITR/GITR siRNA oligo Duplex | 8784 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500598 | Pre-made Rat Tnfrsf18 siRNA oligo Duplex | 500598 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21936 | Pre-made Mouse Tnfrsf18/AITR/Gitr siRNA oligo Duplex | 21936 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699559 | Pre-made Cynomolgus/Rhesus macaque TNFRSF18 siRNA oligo Duplex | 699559 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083251 | Pre-made Cat/Feline TNFRSF18 siRNA oligo Duplex | 101083251 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo606971 | Pre-made Dog/Canine TNFRSF18/GITR siRNA oligo Duplex | 606971 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo516256 | Pre-made Bovines/Cattle TNFRSF18 siRNA oligo Duplex | 516256 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066195 | Pre-made Equine/Horse TNFRSF18 siRNA oligo Duplex | 100066195 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TNFRSF18/CD357 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T15344-Ab | Human | Anti-Human TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T15344-Ab | Rat | Anti-Rat TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T15344-Ab | Mouse | Anti-Mouse TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T15344-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T15344-Ab | Cat/Feline | Anti-Cat/Feline TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T15344-Ab | Dog/Canine | Anti-Dog/Canine TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T15344-Ab | Bovines/Cattle | Anti-Bovines/Cattle TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T15344-Ab | Equine/Horse | Anti-Equine/Horse TNFRSF18/CD357 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
TNFRSF18/CD357 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T15344-Ag | Human | Human TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T15344-Ag | Rat | Rat TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T15344-Ag | Mouse | Mouse TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T15344-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T15344-Ag | Cat/Feline | Cat/Feline TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T15344-Ag | Dog/Canine | Dog/Canine TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T15344-Ag | Bovines/Cattle | Bovines/Cattle TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T15344-Ag | Equine/Horse | Equine/Horse TNFRSF18/CD357 VLP (virus-like particle) | HEK293 | Products Developing |
