Caspase 10/p12/CASP10 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Caspase 10/p12/CASP10 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]

Target ID GM-T14894
Target Name Caspase 10/p12/CASP10
Gene Group ldentifer
(Target Gene ID in Homo species)
843
Gene ID 100068201 (Equus caballus), 101085995 (Felis catus), 488472 (Canis lupus familiaris), 701295 (Macaca mulatta)
843 (Homo sapiens)
Target Alternative Names CASP10,MCH4,ALPS2,FLICE2,FLICE-2
Uniprot Accession Q92851
Uniprot Entry Name
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Apoptosis, RIG-I-like receptor signaling pathway, TNF signaling pathway, Tuberculosis, Hepatitis B
Gene Ensembl ENSECAG00000024244, ENSCAFG00845029977, ENSMMUG00000031297, ENSG00000003400
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of Caspase 10/p12/CASP10 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP000708Human CASP10/ALPS2/FLICE2 Lentivirus plasmidNM_032977843HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP000708Human CASP10/ALPS2/FLICE2 Lentivirus particleNM_032977843HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


Caspase 10/p12/CASP10 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo843Pre-made Human CASP10/MCH4/ALPS2 siRNA oligo Duplex843HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo701295Pre-made Cynomolgus/Rhesus macaque CASP10 siRNA oligo Duplex701295Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101085995Pre-made Cat/Feline CASP10 siRNA oligo Duplex101085995Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo488472Pre-made Dog/Canine CASP10 siRNA oligo Duplex488472Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo100068201Pre-made Equine/Horse CASP10 siRNA oligo Duplex100068201Equine/HorseIn-vitro grade; in-vivo gradeDetail


Caspase 10/p12/CASP10 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T14894-AbHumanAnti-Human Caspase 10/p12/CASP10 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T14894-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Caspase 10/p12/CASP10 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T14894-AbCat/FelineAnti-Cat/Feline Caspase 10/p12/CASP10 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T14894-AbDog/CanineAnti-Dog/Canine Caspase 10/p12/CASP10 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T14894-AbEquine/HorseAnti-Equine/Horse Caspase 10/p12/CASP10 monoclonal antibodymabTherapeutics Target antibodyDetail


Caspase 10/p12/CASP10 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T14894-AgHumanHuman Caspase 10/p12/CASP10 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T14894-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Caspase 10/p12/CASP10 recombinant proteinMammalian cellDetail
GM-Tg-felg-T14894-AgCat/FelineCat/Feline Caspase 10/p12/CASP10 recombinant proteinMammalian cellDetail
GM-Tg-cang-T14894-AgDog/CanineDog/Canine Caspase 10/p12/CASP10 recombinant proteinMammalian cellDetail
GM-Tg-equg-T14894-AgEquine/HorseEquine/Horse Caspase 10/p12/CASP10 recombinant proteinMammalian cellDetail