Explore CD40LG/CD154 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T14755
|
| Target Name |
CD40LG/CD154
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
959
|
| Gene ID |
100054624 (Equus caballus), 21947 (Mus musculus), 403468 (Canis lupus familiaris), 493850 (Felis catus)
574160 (Macaca mulatta), 84349 (Rattus norvegicus), 959 (Homo sapiens)
|
| Target Alternative Names |
CD154,CD40 ligand,CD40-L,CD40L,CD40LG,Cd40l,Cd40lg,HIGM1,IGM,IMD3,Ly-62,Ly62,T-BAM,T-cell antigen Gp39,TNF-related activation protein (TRAP),TNFSF5,TNLG8B,TRAP,Tnfsf5,Tnlg8b,Tumor necrosis factor ligand superfamily member 5,cd154,gp39,hCD40L
|
| Uniprot Accession |
P27548,O97626,O97605,P63304,Q9Z2V2,P29965
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Cell adhesion molecules, T cell receptor signaling pathway, Intestinal immune network for IgA production, Malaria, Toxoplasmosis, Asthma, Autoimmune thyroid disease, Allograft rejection, Viral myocarditis, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000011392, ENSMUSG00000031132, ENSCAFG00845029290, ENSMMUG00000013773, ENSG00000102245
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD40LG/CD154 cDNA Clones/ORF Plasmid
CD40LG/CD154 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo959 | Pre-made Human CD40LG/IGM/IMD3 siRNA oligo Duplex | 959 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84349 | Pre-made Rat Cd40lg/Cd40l/Tnfsf5 siRNA oligo Duplex | 84349 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21947 | Pre-made Mouse Cd40lg/IGM/IMD3 siRNA oligo Duplex | 21947 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574160 | Pre-made Cynomolgus/Rhesus macaque CD40LG/CD40L siRNA oligo Duplex | 574160 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493850 | Pre-made Cat/Feline CD40LG/CD154/CD40L siRNA oligo Duplex | 493850 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403468 | Pre-made Dog/Canine CD40LG/CD154/TNFSF5 siRNA oligo Duplex | 403468 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054624 | Pre-made Equine/Horse CD40LG/cd154/TNLG8B siRNA oligo Duplex | 100054624 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD40LG/CD154 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T14755-Ab | Human | Anti-Human CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T14755-Ab | Rat | Anti-Rat CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T14755-Ab | Mouse | Anti-Mouse CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T14755-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T14755-Ab | Cat/Feline | Anti-Cat/Feline CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T14755-Ab | Dog/Canine | Anti-Dog/Canine CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T14755-Ab | Equine/Horse | Anti-Equine/Horse CD40LG/CD154 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CD40LG/CD154 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T14755-Ag | Human | Human CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T14755-Ag | Rat | Rat CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T14755-Ag | Mouse | Mouse CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T14755-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T14755-Ag | Cat/Feline | Cat/Feline CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T14755-Ag | Dog/Canine | Dog/Canine CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T14755-Ag | Equine/Horse | Equine/Horse CD40LG/CD154 VLP (virus-like particle) | HEK293 | Products Developing |
