SIRT1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SIRT1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

Target ID GM-T14731
Target Name SIRT1
Gene Group ldentifer
（Target Gene ID in Homo species) 		23411
Gene ID 100072571 (Equus caballus), 101087610 (Felis catus), 23411 (Homo sapiens), 309757 (Rattus norvegicus)
489012 (Canis lupus familiaris), 613629 (Bos taurus), 695682 (Macaca mulatta), 93759 (Mus musculus)
Target Alternative Names NAD-dependent protein deacetylase sirtuin-1,NAD-dependent protein deacylase sirtuin-1,Regulatory protein SIR2 homolog 1,SIR2,SIR2-like protein 1 (hSIR2),SIR2L1,SIR2alpha,SIRT1,Sir2,Sir2a,Sir2alpha,Sirt1,hSIRT1,sirtuin-1
Uniprot Accession Q96EB6,A0A0G2JZ79,Q923E4
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease cancer
Disease from KEGG Metabolic pathways, FoxO signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Alcoholic liver disease, Amphetamine addiction
Gene Ensembl ENSECAG00000013909, ENSG00000096717, ENSCAFG00845001191, ENSBTAG00000014023, ENSMMUG00000030531, ENSMUSG00000020063
Target Classification Epigenetic, Tumor-associated antigen (TAA)


Pre-made viral vector of SIRT1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
vGMLV000931Human SIRT1/SIR2/SIR2alpha Lentivirus particleNM_012238.523411HumanLentivirus particleNullNullCMVDetail
pGMAD000579Human SIRT1/SIR2/SIR2alpha Adenovirus plasmidNM_012238.423411HumanAdenovirus plasmidRFP3xflag (C-Terminal)EF1Detail
pGMLV000135Human SIRT1/SIR2/SIR2alpha Lentivirus plasmidNM_012238.423411HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000017Human SIRT1/SIR2/SIR2alpha Mammalian (Non-Viral Vector) plasmidNM_012238.423411HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000135Human SIRT1/SIR2/SIR2alpha Lentivirus particleNM_012238.423411HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPh-275Human SIRT1/SIR2/SIR2alpha Adenovirus plasmidNM_012238.423411HumanAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMLP-SPh-135Human SIRT1/SIR2/SIR2alpha Lentivirus plasmidNM_012238.423411HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP000577Human SIRT1/SIR2/SIR2alpha Adenovirus plasmidNM_01223823411HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAD000579Human SIRT1/SIR2/SIR2alpha Adenovirus particleNM_012238.423411HumanAdenovirus particleRFP3xflag (C-Terminal)EF1Detail
vGMLV000525Human SIRT1/SIR2/SIR2alpha Lentivirus particleNM_012238.423411HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMPC001352Human SIRT1/SIR2/SIR2alpha Mammalian (Non-Viral Vector) plasmidNM_012238.523411HumanMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAP000577Human SIRT1/SIR2/SIR2alpha Adenovirus particleNM_01223823411HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
vGMLP-SPh-135Human SIRT1/SIR2/SIR2alpha Lentivirus particleNM_012238.423411HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000525Human SIRT1/SIR2/SIR2alpha Lentivirus plasmidNM_012238.423411HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000463Human SIRT1/SIR2/SIR2alpha Adenovirus particleNM_012238.423411HumanAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
pGMAD000463Human SIRT1/SIR2/SIR2alpha Adenovirus plasmidNM_012238.423411HumanAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAP-SPh-275Human SIRT1/SIR2/SIR2alpha Adenovirus particleNM_012238.423411HumanAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMLV000931Human SIRT1/SIR2/SIR2alpha Lentivirus plasmidNM_012238.523411HumanLentivirus plasmidNullNullCMVDetail
vGMAD001456Rat Sirt1/Sir2 Adenovirus particleNM_001414959.1309757RatAdenovirus particleNull3xflag (C-Terminal)CMVDetail
pGMPC000074Rat Sirt1 Mammalian (Non-Viral Vector) plasmidXM_017601788.1309757RatMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAAV000201Rat Sirt1 Adeno-associate virus(AAV) particleXM_017601788.1309757RatAdeno-associate virus(AAV) particleGFP3xflag (C-Terminal)CMVDetail
pGMLV001119Rat sirt1/Sir2 Lentivirus plasmidNM_001372090.1309757RatLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV000452Rat Sirt1/Sir2 Adeno-associate virus(AAV) particleNM_001372090309757RatAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000529Rat Sirt1 Adenovirus particleXM_017601789309757RatAdenovirus particleNull3xflag (C-Terminal)CMVDetail
vGMLV001119Rat sirt1/Sir2 Lentivirus particleNM_001372090.1309757RatLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001041Rat Sirt1/Sir2 Adeno-associate virus(AAV) plasmidNM_001372090.1309757RatAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001020Rat Sirt1/Sir2 Adeno-associate virus(AAV) plasmidNM_001372090.1309757RatAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001020Rat Sirt1/Sir2 Adeno-associate virus(AAV) particleNM_001372090.1309757RatAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001041Rat Sirt1/Sir2 Adeno-associate virus(AAV) particleNM_001372090.1309757RatAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000201Rat Sirt1 Adeno-associate virus(AAV) plasmidXM_017601788.1309757RatAdeno-associate virus(AAV) plasmidGFP3xflag (C-Terminal)CMVDetail
pGMAD001456Rat Sirt1/Sir2 Adenovirus plasmidNM_001414959.1309757RatAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMAD000529Rat Sirt1 Adenovirus plasmidXM_017601789309757RatAdenovirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMAAV000452Rat Sirt1/Sir2 Adeno-associate virus(AAV) plasmidNM_001372090309757RatAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000537Mouse Sirt1/AA673258/Sir2 Adenovirus particleNM_01981293759MouseAdenovirus particleFirefly luciferase3xflag (C-Terminal)EF1Detail
pGMLV000090Mouse Sirt1/AA673258/Sir2 Lentivirus plasmidNM_019812.393759MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMAD000630Mouse Sirt1/AA673258/Sir2 Adenovirus particleNM_019812.393759MouseAdenovirus particleGFP3xflag (C-Terminal)EF1Detail
vGMAD001190Mouse Sirt1/AA673258/Sir2 Adenovirus particleNM_019812.393759MouseAdenovirus particlemCherry3xflag (C-Terminal)EF1Detail
vGMAAV000420Mouse Sirt1/AA673258/Sir2 Adeno-associate virus(AAV) particleNM_019812.393759MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001424Mouse Sirt1/Sir2/Sir2a Adeno-associate virus(AAV) particleNM_019812.393759MouseAdeno-associate virus(AAV) particleNull3xflag (C-Terminal)CAGDetail
vGMAAV001583Mouse Sirt1/Sir2/Sir2a Adeno-associate virus(AAV) particleNM_019812.393759MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)TBGDetail
vGMLP-SPm-123Mouse Sirt1/AA673258/Sir2 Lentivirus particleNM_01981293759MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV000751Mouse Sirt1/AA673258/S Adeno-associate virus(AAV) particleNM_019812.393759MouseAdeno-associate virus(AAV) particleNullNullCTNTDetail
pGMPC001177Mouse Sirt1/AA673258/Sir2 Mammalian (Non-Viral Vector) plasmidNM_019812.393759MouseMammalian (Non-Viral Vector) plasmidZsGreen6xHis (C-Terminal)CMVDetail
vGMAP-SPm-250Mouse Sirt1/AA673258/Sir2 Adenovirus particleNM_01981293759MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
pGMAAV001424Mouse Sirt1/Sir2/Sir2a Adeno-associate virus(AAV) plasmidNM_019812.393759MouseAdeno-associate virus(AAV) plasmidNull3xflag (C-Terminal)CAGDetail
pGMLV000581Mouse Sirt1/AA673258/Sir2 Lentivirus plasmidNM_019812.393759MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV000831Mouse Sirt1/AA673258/Sir2 Lentivirus plasmidNM_019812.393759MouseLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMAD000537Mouse Sirt1/AA673258/Sir2 Adenovirus plasmidNM_01981293759MouseAdenovirus plasmidFirefly luciferase3xflag (C-Terminal)EF1Detail
pGMAD000630Mouse Sirt1/AA673258/Sir2 Adenovirus plasmidNM_019812.393759MouseAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
pGMAD001190Mouse Sirt1/AA673258/Sir2 Adenovirus plasmidNM_019812.393759MouseAdenovirus plasmidmCherry3xflag (C-Terminal)EF1Detail
pGMAAV000420Mouse Sirt1/AA673258/Sir2 Adeno-associate virus(AAV) plasmidNM_019812.393759MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000751Mouse Sirt1/AA673258/S Adeno-associate virus(AAV) plasmidNM_019812.393759MouseAdeno-associate virus(AAV) plasmidNullNullCTNTDetail
pGMAAV001583Mouse Sirt1/Sir2/Sir2a Adeno-associate virus(AAV) plasmidNM_019812.393759MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)TBGDetail
vGMLV000831Mouse Sirt1/AA673258/Sir2 Lentivirus particleNM_019812.393759MouseLentivirus particleNull3xflag (C-Terminal)CMVDetail
pGMLP-SPm-123Mouse Sirt1/AA673258/Sir2 Lentivirus plasmidNM_01981293759MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAP-SPm-250Mouse Sirt1/AA673258/Sir2 Adenovirus plasmidNM_01981293759MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC000152Mouse Sirt1/AA673258/Sir2 Mammalian (Non-Viral Vector) plasmidNM_019812.393759MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMPC000553Mouse Sirt1/AA673258/S Mammalian (Non-Viral Vector) plasmidNM_019812.393759MouseMammalian (Non-Viral Vector) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC001540Mouse Sirt1/Sir2/Sir2a Mammalian (Non-Viral Vector) plasmidNM_019812.393759MouseMammalian (Non-Viral Vector) plasmidNull6xHis (C-Terminal)CMVDetail
pGMPC001700Mouse Sirt1/Sir2/Sir2a Mammalian (Non-Viral Vector) plasmidNM_019812.393759MouseMammalian (Non-Viral Vector) plasmidEGFPNullEF1Detail
vGMLV000090Mouse Sirt1/AA673258/Sir2 Lentivirus particleNM_019812.393759MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV000581Mouse Sirt1/AA673258/Sir2 Lentivirus particleNM_019812.393759MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAD000091Cattle SIRT1 Adenovirus plasmidNM_001192980613629CattleAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAD000091Cattle SIRT1 Adenovirus particleNM_001192980613629CattleAdenovirus particleGFP3xflag (C-Terminal)EF1Detail


SIRT1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo23411Pre-made Human SIRT1/SIR2/SIR2L1 siRNA oligo Duplex23411HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo309757Pre-made Rat Sirt1/Sir2 siRNA oligo Duplex309757RatIn-vitro grade; in-vivo gradeDetail
pGMoligo93759Pre-made Mouse Sirt1/Sir2/Sir2a siRNA oligo Duplex93759MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo695682Pre-made Cynomolgus/Rhesus macaque SIRT1 siRNA oligo Duplex695682Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101087610Pre-made Cat/Feline SIRT1 siRNA oligo Duplex101087610Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo489012Pre-made Dog/Canine SIRT1/sirtuin-1 siRNA oligo Duplex489012Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo613629Pre-made Bovines/Cattle SIRT1 siRNA oligo Duplex613629Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100072571Pre-made Equine/Horse SIRT1 siRNA oligo Duplex100072571Equine/HorseIn-vitro grade; in-vivo gradeDetail


SIRT1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T14731-AbHumanAnti-Human SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T14731-AbRatAnti-Rat SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T14731-AbMouseAnti-Mouse SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T14731-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T14731-AbCat/FelineAnti-Cat/Feline SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T14731-AbDog/CanineAnti-Dog/Canine SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T14731-AbBovines/CattleAnti-Bovines/Cattle SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T14731-AbEquine/HorseAnti-Equine/Horse SIRT1 monoclonal antibodymabTherapeutics Target antibodyDetail


SIRT1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T14731-AgHumanHuman SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-rg-T14731-AgRatRat SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-mg-T14731-AgMouseMouse SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T14731-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-felg-T14731-AgCat/FelineCat/Feline SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-cang-T14731-AgDog/CanineDog/Canine SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T14731-AgBovines/CattleBovines/Cattle SIRT1 recombinant proteinMammalian cellDetail
GM-Tg-equg-T14731-AgEquine/HorseEquine/Horse SIRT1 recombinant proteinMammalian cellDetail