Explore EBI3/IL35 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells. [provided by RefSeq, Sep 2008]
| Target ID |
GM-T02231
|
| Target Name |
EBI3/IL35
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10148
|
| Gene ID |
100063061 (Equus caballus), 101101032 (Felis catus), 10148 (Homo sapiens), 485043 (Canis lupus familiaris)
50498 (Mus musculus), 514933 (Bos taurus), 680609 (Rattus norvegicus), 721832 (Macaca mulatta)
|
| Target Alternative Names |
EBI-3,EBI3,Ebi3,Epstein-Barr virus-induced gene 3 protein (EBV-induced gene 3 protein),IL-27,IL-27 subunit beta,IL-27B,IL27B,IL35,IL35B,Interleukin-27 subunit beta
|
| Uniprot Accession |
Q14213,O35228
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Th17 cell differentiation
|
| Gene Ensembl |
ENSECAG00000018667, ENSG00000105246, ENSCAFG00845006245, ENSMUSG00000003206, ENSBTAG00000012829, ENSMMUG00000028928
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of EBI3/IL35 cDNA Clones/ORF Plasmid
EBI3/IL35 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10148 | Pre-made Human EBI3/IL27B/IL35B siRNA oligo Duplex | 10148 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo680609 | Pre-made Rat Ebi3 siRNA oligo Duplex | 680609 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50498 | Pre-made Mouse Ebi3/EBI-3/IL-27 siRNA oligo Duplex | 50498 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721832 | Pre-made Cynomolgus/Rhesus macaque EBI3 siRNA oligo Duplex | 721832 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101032 | Pre-made Cat/Feline EBI3 siRNA oligo Duplex | 101101032 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485043 | Pre-made Dog/Canine EBI3 siRNA oligo Duplex | 485043 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514933 | Pre-made Bovines/Cattle EBI3 siRNA oligo Duplex | 514933 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063061 | Pre-made Equine/Horse EBI3 siRNA oligo Duplex | 100063061 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EBI3/IL35 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T02231-Ab | Human | Anti-Human EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T02231-Ab | Rat | Anti-Rat EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T02231-Ab | Mouse | Anti-Mouse EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T02231-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T02231-Ab | Cat/Feline | Anti-Cat/Feline EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T02231-Ab | Dog/Canine | Anti-Dog/Canine EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T02231-Ab | Bovines/Cattle | Anti-Bovines/Cattle EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T02231-Ab | Equine/Horse | Anti-Equine/Horse EBI3/IL35 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EBI3/IL35 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T02231-Ag | Human | Human EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T02231-Ag | Rat | Rat EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T02231-Ag | Mouse | Mouse EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T02231-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T02231-Ag | Cat/Feline | Cat/Feline EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T02231-Ag | Dog/Canine | Dog/Canine EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T02231-Ag | Bovines/Cattle | Bovines/Cattle EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T02231-Ag | Equine/Horse | Equine/Horse EBI3/IL35 VLP (virus-like particle) | HEK293 | Products Developing |
