5 Lipoxygenase/ALOX5/5-LOX Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore 5 Lipoxygenase/ALOX5/5-LOX gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Pre-made viral vector of 5 Lipoxygenase/ALOX5/5-LOX cDNA Clones/ORF Plasmid

5 Lipoxygenase/ALOX5/5-LOX siRNA/miRNA/oligo for RNA interfence (RNAi)

5 Lipoxygenase/ALOX5/5-LOX antibody/GMab

5 Lipoxygenase/ALOX5/5-LOX recombinant protein