Explore PRDM12 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]
Target ID |
GM-SE1494
|
Target Name |
PRDM12
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
59335
|
Gene ID |
100146306 (Equus caballus), 111557554 (Felis catus), 119873358 (Canis lupus familiaris), 381359 (Mus musculus) 59335 (Homo sapiens), 618320 (Bos taurus), 688699 (Rattus norvegicus), 716040 (Macaca mulatta)
|
Target Alternative Names |
PRDM12,Prdm12,Gm998,PFM9,HSAN8
|
Uniprot Accession |
A2AJ77,Q9H4Q4
|
Uniprot Entry Name |
|
Protein Sub-location |
Secreted Protein/Potential Cytokines
|
Category |
|
Disease |
|
Disease from KEGG |
|
Gene Ensembl |
ENSECAG00000005933, ENSCAFG00845021131, ENSMUSG00000079466, ENSG00000130711, ENSBTAG00000023797, ENSMMUG00000059085
|
Target Classification |
|
PRDM12 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo59335 | Pre-made Human PRDM12/PFM9/HSAN8 siRNA oligo Duplex | 59335 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo688699 | Pre-made Rat Prdm12 siRNA oligo Duplex | 688699 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo381359 | Pre-made Mouse Prdm12/Gm998 siRNA oligo Duplex | 381359 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo716040 | Pre-made Cynomolgus/Rhesus macaque PRDM12 siRNA oligo Duplex | 716040 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo111557554 | Pre-made Cat/Feline PRDM12 siRNA oligo Duplex | 111557554 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo119873358 | Pre-made Dog/Canine PRDM12 siRNA oligo Duplex | 119873358 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo618320 | Pre-made Bovines/Cattle PRDM12 siRNA oligo Duplex | 618320 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100146306 | Pre-made Equine/Horse PRDM12 siRNA oligo Duplex | 100146306 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRDM12 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-SE1494-Ab | Human | Anti-Human PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-rg-SE1494-Ab | Rat | Anti-Rat PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-mg-SE1494-Ab | Mouse | Anti-Mouse PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cynog-SE1494-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-felg-SE1494-Ab | Cat/Feline | Anti-Cat/Feline PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cang-SE1494-Ab | Dog/Canine | Anti-Dog/Canine PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-bovg-SE1494-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-equg-SE1494-Ab | Equine/Horse | Anti-Equine/Horse PRDM12 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PRDM12 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-SE1494-Ag | Human | Human PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-SE1494-Ag | Rat | Rat PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-SE1494-Ag | Mouse | Mouse PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-SE1494-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-SE1494-Ag | Cat/Feline | Cat/Feline PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-SE1494-Ag | Dog/Canine | Dog/Canine PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-SE1494-Ag | Bovines/Cattle | Bovines/Cattle PRDM12 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-SE1494-Ag | Equine/Horse | Equine/Horse PRDM12 recombinant protein | Mammalian cell | Detail |