Recombinant multi-species PRDM12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRDM12 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]
The Alternative Names of target: PRDM12,PR domain zinc finger protein 12,PR domain-containing protein 12,PFM9,HSAN8

Target products collectionGo to PRDM12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1494-Ab-1/ GM-Tg-hg-SE1494-Ab-2 Human PRDM12 protein Human
GM-Tg-rg-SE1494-Ab-1/ GM-Tg-rg-SE1494-Ab-2 Rat PRDM12 protein Rat
GM-Tg-mg-SE1494-Ab-1/ GM-Tg-mg-SE1494-Ab-2 Mouse PRDM12 protein Mouse
GM-Tg-cynog-SE1494-Ab-1/ GM-Tg-cynog-SE1494-Ab-2 Cynomolgus/Rhesus macaque PRDM12 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1494-Ab-1/ GM-Tg-felg-SE1494-Ab-2 Feline PRDM12 protein Feline
GM-Tg-cang-SE1494-Ab-1/ GM-Tg-cang-SE1494-Ab-2 Canine PRDM12 protein Canine
GM-Tg-bovg-SE1494-Ab-1/ GM-Tg-bovg-SE1494-Ab-2 Bovine PRDM12 protein Bovine
GM-Tg-equg-SE1494-Ab-1/ GM-Tg-equg-SE1494-Ab-2 Equine PRDM12 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1494-Ab-1/ GM-Tg-hg-SE1494-Ab-2; GM-Tg-rg-SE1494-Ab-1/ GM-Tg-rg-SE1494-Ab-2;
GM-Tg-mg-SE1494-Ab-1/ GM-Tg-mg-SE1494-Ab-2; GM-Tg-cynog-SE1494-Ab-1/ GM-Tg-cynog-SE1494-Ab-2;
GM-Tg-felg-SE1494-Ab-1/ GM-Tg-felg-SE1494-Ab-2; GM-Tg-cang-SE1494-Ab-1/ GM-Tg-cang-SE1494-Ab-2;
GM-Tg-bovg-SE1494-Ab-1/ GM-Tg-bovg-SE1494-Ab-2; GM-Tg-equg-SE1494-Ab-1/ GM-Tg-equg-SE1494-Ab-2
Products Name PRDM12 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRDM12
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRDM12 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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