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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| Target ID |
GM-SE1491
|
| Target Name |
AANAT
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
15
|
| Gene ID |
100058770 (Equus caballus), 101098178 (Felis catus), 11298 (Mus musculus), 15 (Homo sapiens)
25120 (Rattus norvegicus), 483331 (Canis lupus familiaris), 706924 (Macaca mulatta)
|
| Target Alternative Names |
AA-NAT,AANAT,Aanat,Aralkylamine N-acetyltransferase (AA-NAT),DSPS,Nat-2,Nat4,SNAT,Serotonin N-acetyltransferase,Serotonin acetylase,Snat
|
| Uniprot Accession |
O88816,Q16613,Q64666,O97756
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000022577, ENSMUSG00000020804, ENSG00000129673, ENSCAFG00845017611, ENSMMUG00000018970
|
AANAT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo15 | Pre-made Human AANAT/DSPS/SNAT siRNA oligo Duplex | 15 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25120 | Pre-made Rat Aanat/Nat4/AA-NAT siRNA oligo Duplex | 25120 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11298 | Pre-made Mouse Aanat/Nat4/Snat siRNA oligo Duplex | 11298 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706924 | Pre-made Cynomolgus/Rhesus macaque AANAT siRNA oligo Duplex | 706924 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098178 | Pre-made Cat/Feline AANAT siRNA oligo Duplex | 101098178 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483331 | Pre-made Dog/Canine AANAT siRNA oligo Duplex | 483331 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058770 | Pre-made Equine/Horse AANAT siRNA oligo Duplex | 100058770 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AANAT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1491-Ab | Human | Anti-Human AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1491-Ab | Rat | Anti-Rat AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1491-Ab | Mouse | Anti-Mouse AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1491-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1491-Ab | Cat/Feline | Anti-Cat/Feline AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1491-Ab | Dog/Canine | Anti-Dog/Canine AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1491-Ab | Equine/Horse | Anti-Equine/Horse AANAT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
AANAT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1491-Ag | Human | Human AANAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1491-Ag | Rat | Rat AANAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1491-Ag | Mouse | Mouse AANAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1491-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AANAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1491-Ag | Cat/Feline | Cat/Feline AANAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1491-Ag | Dog/Canine | Dog/Canine AANAT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1491-Ag | Equine/Horse | Equine/Horse AANAT recombinant protein | Mammalian cell | Detail |
