Explore Thyroglobulin/TG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
| Target ID |
GM-SE1335
|
| Target Name |
Thyroglobulin/TG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7038
|
| Gene ID |
100058029 (Equus caballus), 101088550 (Felis catus), 21819 (Mus musculus), 24826 (Rattus norvegicus)
280706 (Bos taurus), 482047 (Canis lupus familiaris), 701756 (Macaca mulatta), 7038 (Homo sapiens)
|
| Target Alternative Names |
AITD3,TG,TGN,Tg,Tgn,Thyroglobulin,cog
|
| Uniprot Accession |
O08710,P06882,P01267,P01266
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Diagnostics Biomarker
|
| Disease |
thyroid cancer
|
| Disease from KEGG |
Thyroid hormone synthesis, Autoimmune thyroid disease
|
| Gene Ensembl |
ENSECAG00000018808, ENSMUSG00000053469, ENSBTAG00000007823, ENSCAFG00845008772, ENSMMUG00000041378, ENSG00000042832
|
Thyroglobulin/TG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7038 | Pre-made Human TG/TGN/AITD3 siRNA oligo Duplex | 7038 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24826 | Pre-made Rat Tg/Tgn siRNA oligo Duplex | 24826 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21819 | Pre-made Mouse Tg/Tgn/cog siRNA oligo Duplex | 21819 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701756 | Pre-made Cynomolgus/Rhesus macaque TG siRNA oligo Duplex | 701756 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088550 | Pre-made Cat/Feline TG siRNA oligo Duplex | 101088550 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482047 | Pre-made Dog/Canine TG siRNA oligo Duplex | 482047 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280706 | Pre-made Bovines/Cattle TG siRNA oligo Duplex | 280706 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058029 | Pre-made Equine/Horse TG siRNA oligo Duplex | 100058029 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Thyroglobulin/TG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1335-Ab | Human | Anti-Human Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-SE1335-Ab | Rat | Anti-Rat Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-SE1335-Ab | Mouse | Anti-Mouse Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-SE1335-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-SE1335-Ab | Cat/Feline | Anti-Cat/Feline Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-SE1335-Ab | Dog/Canine | Anti-Dog/Canine Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-SE1335-Ab | Bovines/Cattle | Anti-Bovines/Cattle Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-SE1335-Ab | Equine/Horse | Anti-Equine/Horse Thyroglobulin/TG monoclonal antibody | mab | FACS/Biofunctional Antibody, Diagnostic target antibody | Detail |
Thyroglobulin/TG recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1335-Ag | Human | Human Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1335-Ag | Rat | Rat Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1335-Ag | Mouse | Mouse Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1335-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1335-Ag | Cat/Feline | Cat/Feline Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1335-Ag | Dog/Canine | Dog/Canine Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1335-Ag | Bovines/Cattle | Bovines/Cattle Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1335-Ag | Equine/Horse | Equine/Horse Thyroglobulin/TG recombinant protein | Mammalian cell | Detail |
