Explore SPINK5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
| Target ID |
GM-SE1312
|
| Target Name |
SPINK5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11005
|
| Gene ID |
100071873 (Equus caballus), 101086696 (Felis catus), 11005 (Homo sapiens), 361319 (Rattus norvegicus)
478055 (Canis lupus familiaris), 526637 (Bos taurus), 709424 (Macaca mulatta), 72432 (Mus musculus)
|
| Target Alternative Names |
2310065D10Rik,LEKT1,LEKTI,LETK1,LETKI,Lympho-epithelial Kazal-type-related inhibitor (LEKTI),NETS,NS,SPINK5,Serine protease inhibitor Kazal-type 5,Spink5,VAKT1,VAKTI
|
| Uniprot Accession |
Q9NQ38
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSECAG00000000651, ENSG00000133710, ENSCAFG00845025212, ENSBTAG00000019140, ENSMMUG00000017900, ENSMUSG00000055561
|
Pre-made viral vector of SPINK5 cDNA Clones/ORF Plasmid
SPINK5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11005 | Pre-made Human SPINK5/NS/NETS siRNA oligo Duplex | 11005 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo361319 | Pre-made Rat Spink5 siRNA oligo Duplex | 361319 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo72432 | Pre-made Mouse Spink5/LEKT1/LETK1 siRNA oligo Duplex | 72432 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709424 | Pre-made Cynomolgus/Rhesus macaque SPINK5 siRNA oligo Duplex | 709424 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086696 | Pre-made Cat/Feline SPINK5 siRNA oligo Duplex | 101086696 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478055 | Pre-made Dog/Canine SPINK5 siRNA oligo Duplex | 478055 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526637 | Pre-made Bovines/Cattle SPINK5 siRNA oligo Duplex | 526637 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071873 | Pre-made Equine/Horse SPINK5 siRNA oligo Duplex | 100071873 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SPINK5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1312-Ab | Human | Anti-Human SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1312-Ab | Rat | Anti-Rat SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1312-Ab | Mouse | Anti-Mouse SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1312-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1312-Ab | Cat/Feline | Anti-Cat/Feline SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1312-Ab | Dog/Canine | Anti-Dog/Canine SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1312-Ab | Bovines/Cattle | Anti-Bovines/Cattle SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1312-Ab | Equine/Horse | Anti-Equine/Horse SPINK5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SPINK5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1312-Ag | Human | Human SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1312-Ag | Rat | Rat SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1312-Ag | Mouse | Mouse SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1312-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1312-Ag | Cat/Feline | Cat/Feline SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1312-Ag | Dog/Canine | Dog/Canine SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1312-Ag | Bovines/Cattle | Bovines/Cattle SPINK5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1312-Ag | Equine/Horse | Equine/Horse SPINK5 recombinant protein | Mammalian cell | Detail |
