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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014]
| Target ID |
GM-SE1292
|
| Target Name |
SLPI
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6590
|
| Gene ID |
101090682 (Felis catus), 20568 (Mus musculus), 6590 (Homo sapiens), 711156 (Macaca mulatta) 84386 (Rattus norvegicus)
|
| Target Alternative Names |
ALK1,ALP,Antileukoproteinase,BLPI,HUSI,HUSI-1,HUSI-I,MPI,Mucus proteinase inhibitor (MPI),Protease inhibitor WAP4,SLPI,Secretory leukocyte protease inhibitor,Seminal proteinase inhibitor,Slpi,WAP four-disulfide core domain protein 4,WAP4,WFDC4
|
| Uniprot Accession |
P97430,P03973
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer, Prostate Cancer
|
| Gene Ensembl |
ENSMUSG00000017002, ENSG00000124107, ENSMMUG00000050091
|
Pre-made viral vector of SLPI cDNA Clones/ORF Plasmid
SLPI siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6590 | Pre-made Human SLPI/ALP/MPI siRNA oligo Duplex | 6590 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84386 | Pre-made Rat Slpi siRNA oligo Duplex | 84386 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20568 | Pre-made Mouse Slpi/ALP siRNA oligo Duplex | 20568 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711156 | Pre-made Cynomolgus/Rhesus macaque SLPI siRNA oligo Duplex | 711156 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090682 | Pre-made Cat/Feline SLPI siRNA oligo Duplex | 101090682 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
SLPI antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1292-Ab | Human | Anti-Human SLPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1292-Ab | Rat | Anti-Rat SLPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1292-Ab | Mouse | Anti-Mouse SLPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1292-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SLPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1292-Ab | Cat/Feline | Anti-Cat/Feline SLPI monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SLPI recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1292-Ag | Human | Human SLPI recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1292-Ag | Rat | Rat SLPI recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1292-Ag | Mouse | Mouse SLPI recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1292-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SLPI recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1292-Ag | Cat/Feline | Cat/Feline SLPI recombinant protein | Mammalian cell | Detail |