Explore Protein Z/PROZ gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| Target ID |
GM-SE1208
|
| Target Name |
Protein Z/PROZ
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8858
|
| Gene ID |
100067119 (Equus caballus), 306608 (Rattus norvegicus), 617946 (Bos taurus), 66901 (Mus musculus) 696982 (Macaca mulatta), 8858 (Homo sapiens)
|
| Target Alternative Names |
1300015B06Rik,PROZ,PZ,Protein Z,Proz,Vitamin K-dependent protein Z
|
| Uniprot Accession |
P00744,Q9CQW3,P22891
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSECAG00000024697, ENSBTAG00000019440, ENSMUSG00000031445, ENSMMUG00000001039, ENSG00000126231
|
Pre-made viral vector of Protein Z/PROZ cDNA Clones/ORF Plasmid
Protein Z/PROZ siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8858 | Pre-made Human PROZ/PZ siRNA oligo Duplex | 8858 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306608 | Pre-made Rat Proz siRNA oligo Duplex | 306608 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo66901 | Pre-made Mouse Proz/1300015B06Rik siRNA oligo Duplex | 66901 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696982 | Pre-made Cynomolgus/Rhesus macaque PROZ siRNA oligo Duplex | 696982 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617946 | Pre-made Bovines/Cattle PROZ siRNA oligo Duplex | 617946 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067119 | Pre-made Equine/Horse PROZ siRNA oligo Duplex | 100067119 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Protein Z/PROZ antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1208-Ab | Human | Anti-Human Protein Z/PROZ monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1208-Ab | Rat | Anti-Rat Protein Z/PROZ monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1208-Ab | Mouse | Anti-Mouse Protein Z/PROZ monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1208-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Protein Z/PROZ monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1208-Ab | Bovines/Cattle | Anti-Bovines/Cattle Protein Z/PROZ monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1208-Ab | Equine/Horse | Anti-Equine/Horse Protein Z/PROZ monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Protein Z/PROZ recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1208-Ag | Human | Human Protein Z/PROZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1208-Ag | Rat | Rat Protein Z/PROZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1208-Ag | Mouse | Mouse Protein Z/PROZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1208-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Protein Z/PROZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1208-Ag | Bovines/Cattle | Bovines/Cattle Protein Z/PROZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1208-Ag | Equine/Horse | Equine/Horse Protein Z/PROZ recombinant protein | Mammalian cell | Detail |