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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]
| Target ID |
GM-SE1165
|
| Target Name |
OXT
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5020
|
| Gene ID |
100856247 (Canis lupus familiaris), 111559702 (Felis catus), 111767489 (Equus caballus), 18429 (Mus musculus) 25504 (Rattus norvegicus), 280888 (Bos taurus), 5020 (Homo sapiens), 717068 (Macaca mulatta)
|
| Target Alternative Names |
OT,OT-NPI,OTNPI,OXT,OXT-NPI,Oxt,Oxy,Oxytocin-neurophysin 1
|
| Uniprot Accession |
P35454,P01179,P01175,P01178
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
cAMP signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway
|
| Gene Ensembl |
ENSECAG00000034091, ENSMUSG00000027301, ENSBTAG00000008026, ENSG00000101405, ENSMMUG00000010678
|
Pre-made viral vector of OXT cDNA Clones/ORF Plasmid
OXT siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5020 | Pre-made Human OXT/OT/OT-NPI siRNA oligo Duplex | 5020 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25504 | Pre-made Rat Oxt siRNA oligo Duplex | 25504 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18429 | Pre-made Mouse Oxt/OT/Oxy siRNA oligo Duplex | 18429 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717068 | Pre-made Cynomolgus/Rhesus macaque OXT siRNA oligo Duplex | 717068 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111559702 | Pre-made Cat/Feline OXT siRNA oligo Duplex | 111559702 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856247 | Pre-made Dog/Canine OXT siRNA oligo Duplex | 100856247 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280888 | Pre-made Bovines/Cattle OXT/OTNPI/OT-NPI siRNA oligo Duplex | 280888 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111767489 | Pre-made Equine/Horse OXT siRNA oligo Duplex | 111767489 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OXT antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1165-Ab | Human | Anti-Human OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1165-Ab | Rat | Anti-Rat OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1165-Ab | Mouse | Anti-Mouse OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1165-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1165-Ab | Cat/Feline | Anti-Cat/Feline OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1165-Ab | Dog/Canine | Anti-Dog/Canine OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1165-Ab | Bovines/Cattle | Anti-Bovines/Cattle OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1165-Ab | Equine/Horse | Anti-Equine/Horse OXT monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
OXT recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1165-Ag | Human | Human OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1165-Ag | Rat | Rat OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1165-Ag | Mouse | Mouse OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1165-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1165-Ag | Cat/Feline | Cat/Feline OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1165-Ag | Dog/Canine | Dog/Canine OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1165-Ag | Bovines/Cattle | Bovines/Cattle OXT recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1165-Ag | Equine/Horse | Equine/Horse OXT recombinant protein | Mammalian cell | Detail |