Explore NPC2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE1133
|
| Target Name |
NPC2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10577
|
| Gene ID |
100051060 (Equus caballus), 101094270 (Felis catus), 10577 (Homo sapiens), 280815 (Bos taurus)
286898 (Rattus norvegicus), 403920 (Canis lupus familiaris), 67963 (Mus musculus), 699881 (Macaca mulatta)
|
| Target Alternative Names |
2700012J19Rik,CE1,EDDM1,Epididymal secretory protein E1,HE1,Human epididymis-specific protein 1 (He1),NPC intracellular cholesterol transporter 2,NPC2,Niemann-Pick disease type C2 protein,Npc2,re1
|
| Uniprot Accession |
P61916,P79345,Q28895,Q9Z0J0
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Lysosome, Cholesterol metabolism
|
| Gene Ensembl |
ENSECAG00000018345, ENSG00000119655, ENSBTAG00000021955, ENSCAFG00845014286, ENSMUSG00000021242, ENSMMUG00000006563
|
Pre-made viral vector of NPC2 cDNA Clones/ORF Plasmid
NPC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10577 | Pre-made Human NPC2/HE1/EDDM1 siRNA oligo Duplex | 10577 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo286898 | Pre-made Rat Npc2/re1 siRNA oligo Duplex | 286898 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo67963 | Pre-made Mouse Npc2/HE1/2700012J19Rik siRNA oligo Duplex | 67963 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699881 | Pre-made Cynomolgus/Rhesus macaque NPC2 siRNA oligo Duplex | 699881 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094270 | Pre-made Cat/Feline NPC2 siRNA oligo Duplex | 101094270 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403920 | Pre-made Dog/Canine NPC2/CE1 siRNA oligo Duplex | 403920 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280815 | Pre-made Bovines/Cattle NPC2/HE1 siRNA oligo Duplex | 280815 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051060 | Pre-made Equine/Horse NPC2 siRNA oligo Duplex | 100051060 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NPC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1133-Ab | Human | Anti-Human NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1133-Ab | Rat | Anti-Rat NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1133-Ab | Mouse | Anti-Mouse NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1133-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1133-Ab | Cat/Feline | Anti-Cat/Feline NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1133-Ab | Dog/Canine | Anti-Dog/Canine NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1133-Ab | Bovines/Cattle | Anti-Bovines/Cattle NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1133-Ab | Equine/Horse | Anti-Equine/Horse NPC2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
NPC2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1133-Ag | Human | Human NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1133-Ag | Rat | Rat NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1133-Ag | Mouse | Mouse NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1133-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1133-Ag | Cat/Feline | Cat/Feline NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1133-Ag | Dog/Canine | Dog/Canine NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1133-Ag | Bovines/Cattle | Bovines/Cattle NPC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1133-Ag | Equine/Horse | Equine/Horse NPC2 recombinant protein | Mammalian cell | Detail |
