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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a ubiquitin-like protein that is conjugated to intracellular target proteins upon activation by interferon-alpha and interferon-beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. [provided by RefSeq, Dec 2012]
| Target ID |
GM-SE1038
|
| Target Name |
ISG15
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9636
|
| Gene ID |
100038882 (Mus musculus), 100066364 (Equus caballus), 100174787 (Felis catus), 100855667 (Canis lupus familiaris) 281871 (Bos taurus), 298693 (Rattus norvegicus), 700141 (Macaca mulatta), 9636 (Homo sapiens)
|
| Target Alternative Names |
G1P2,G1p2,IFI15,IGI15,IMD38,IP17,ISG15,Interferon-induced 15 kDa protein,Interferon-induced 17 kDa protein (IP17),Irfp,Isg15,UCRP,Ubiquitin cross-reactive protein (hUCRP),Ubiquitin-like protein ISG15,hUCRP
|
| Uniprot Accession |
Q64339,O02741,P05161
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer
|
| Disease from KEGG |
RIG-I-like receptor signaling pathway, Human papillomavirus infection, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSMUSG00000035692, ENSECAG00000059003, ENSCAFG00845020316, ENSBTAG00000014707, ENSMMUG00000050757, ENSG00000187608
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of ISG15 cDNA Clones/ORF Plasmid
ISG15 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9636 | Pre-made Human ISG15/G1P2/IP17 siRNA oligo Duplex | 9636 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298693 | Pre-made Rat Isg15/G1p2 siRNA oligo Duplex | 298693 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100038882 | Pre-made Mouse Isg15/G1p2/IP17 siRNA oligo Duplex | 100038882 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700141 | Pre-made Cynomolgus/Rhesus macaque ISG15 siRNA oligo Duplex | 700141 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100174787 | Pre-made Cat/Feline ISG15 siRNA oligo Duplex | 100174787 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855667 | Pre-made Dog/Canine ISG15 siRNA oligo Duplex | 100855667 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281871 | Pre-made Bovines/Cattle ISG15 siRNA oligo Duplex | 281871 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066364 | Pre-made Equine/Horse ISG15 siRNA oligo Duplex | 100066364 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ISG15 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1038-Ab | Human | Anti-Human ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1038-Ab | Rat | Anti-Rat ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1038-Ab | Mouse | Anti-Mouse ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1038-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1038-Ab | Cat/Feline | Anti-Cat/Feline ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1038-Ab | Dog/Canine | Anti-Dog/Canine ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1038-Ab | Bovines/Cattle | Anti-Bovines/Cattle ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1038-Ab | Equine/Horse | Anti-Equine/Horse ISG15 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
ISG15 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1038-Ag | Human | Human ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1038-Ag | Rat | Rat ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1038-Ag | Mouse | Mouse ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1038-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1038-Ag | Cat/Feline | Cat/Feline ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1038-Ag | Dog/Canine | Dog/Canine ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1038-Ag | Bovines/Cattle | Bovines/Cattle ISG15 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1038-Ag | Equine/Horse | Equine/Horse ISG15 recombinant protein | Mammalian cell | Detail |