Explore IL-18BP/IL18BP gene products and cross-species
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
| Target ID |
GM-SE1023
|
| Target Name |
IL-18BP/IL18BP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
10068
|
| Gene ID |
100066161 (Equus caballus), 100144607 (Macaca mulatta), 10068 (Homo sapiens), 101096599 (Felis catus) 16068 (Mus musculus), 476818 (Canis lupus familiaris), 617470 (Bos taurus), 84388 (Rattus norvegicus)
|
| Target Alternative Names |
FVH,IL-18BP,IL18BP,IL18BPa,Igifbp,Il18bp,Interleukin-18-binding protein,MC54L,Tadekinig-alfa
|
| Uniprot Accession |
O95998,Q9Z0M9
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Malignant neoplasm of prostate
|
| Gene Ensembl |
ENSMMUG00000007340, ENSG00000137496, ENSMUSG00000070427, ENSBTAG00000027676
|
Pre-made viral vector of IL-18BP/IL18BP cDNA Clones/ORF Plasmid
IL-18BP/IL18BP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10068 | Pre-made Human IL18BP/FVH/IL18BPa siRNA oligo Duplex | 10068 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84388 | Pre-made Rat Il18bp/Igifbp siRNA oligo Duplex | 84388 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16068 | Pre-made Mouse Il18bp/MC54L/Igifbp siRNA oligo Duplex | 16068 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100144607 | Pre-made Cynomolgus/Rhesus macaque IL18BP siRNA oligo Duplex | 100144607 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096599 | Pre-made Cat/Feline IL18BP siRNA oligo Duplex | 101096599 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476818 | Pre-made Dog/Canine IL18BP siRNA oligo Duplex | 476818 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo617470 | Pre-made Bovines/Cattle IL18BP siRNA oligo Duplex | 617470 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066161 | Pre-made Equine/Horse IL18BP siRNA oligo Duplex | 100066161 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-18BP/IL18BP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1023-Ab | Human | Anti-Human IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE1023-Ab | Rat | Anti-Rat IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE1023-Ab | Mouse | Anti-Mouse IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE1023-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE1023-Ab | Cat/Feline | Anti-Cat/Feline IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE1023-Ab | Dog/Canine | Anti-Dog/Canine IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE1023-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE1023-Ab | Equine/Horse | Anti-Equine/Horse IL-18BP/IL18BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-18BP/IL18BP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1023-Ag | Human | Human IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1023-Ag | Rat | Rat IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1023-Ag | Mouse | Mouse IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1023-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1023-Ag | Cat/Feline | Cat/Feline IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1023-Ag | Dog/Canine | Dog/Canine IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1023-Ag | Bovines/Cattle | Bovines/Cattle IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1023-Ag | Equine/Horse | Equine/Horse IL-18BP/IL18BP recombinant protein | Mammalian cell | Detail |