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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE0959
|
| Target Name |
GREM2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
64388
|
| Gene ID |
100060243 (Equus caballus), 101096531 (Felis catus), 23893 (Mus musculus), 289264 (Rattus norvegicus)
490367 (Canis lupus familiaris), 64388 (Homo sapiens), 708280 (Macaca mulatta)
|
| Target Alternative Names |
BMP antagonist 2,CKTSF1B2,Cysteine knot superfamily 1,DAN domain family member 3,DAND3,GREM2,Grem2,Gremlin-2,Gremlin2,PRDC,Prdc,Protein related to DAN and cerberus,RGD1560008,STHAG9
|
| Uniprot Accession |
O88273,Q9H772
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
TGF-beta signaling pathway
|
| Gene Ensembl |
ENSECAG00000003167, ENSMUSG00000050069, ENSCAFG00845004033, ENSG00000180875, ENSMMUG00000064824
|
Pre-made viral vector of GREM2 cDNA Clones/ORF Plasmid
GREM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo64388 | Pre-made Human GREM2/PRDC/DAND3 siRNA oligo Duplex | 64388 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289264 | Pre-made Rat Grem2/RGD1560008 siRNA oligo Duplex | 289264 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo23893 | Pre-made Mouse Grem2/Prdc/Gremlin2 siRNA oligo Duplex | 23893 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708280 | Pre-made Cynomolgus/Rhesus macaque GREM2 siRNA oligo Duplex | 708280 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096531 | Pre-made Cat/Feline GREM2 siRNA oligo Duplex | 101096531 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490367 | Pre-made Dog/Canine GREM2 siRNA oligo Duplex | 490367 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060243 | Pre-made Equine/Horse GREM2 siRNA oligo Duplex | 100060243 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GREM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0959-Ab | Human | Anti-Human GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0959-Ab | Rat | Anti-Rat GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0959-Ab | Mouse | Anti-Mouse GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE0959-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE0959-Ab | Cat/Feline | Anti-Cat/Feline GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE0959-Ab | Dog/Canine | Anti-Dog/Canine GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE0959-Ab | Equine/Horse | Anti-Equine/Horse GREM2 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GREM2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0959-Ag | Human | Human GREM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0959-Ag | Rat | Rat GREM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0959-Ag | Mouse | Mouse GREM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0959-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GREM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0959-Ag | Cat/Feline | Cat/Feline GREM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0959-Ag | Dog/Canine | Dog/Canine GREM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0959-Ag | Equine/Horse | Equine/Horse GREM2 recombinant protein | Mammalian cell | Detail |
