Explore GDF1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]
| Target ID |
GM-SE0938
|
| Target Name |
GDF1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2657
|
| Gene ID |
100686938 (Canis lupus familiaris), 101096297 (Felis catus), 104968455 (Bos taurus), 111769683 (Equus caballus) 14559 (Mus musculus), 2657 (Homo sapiens), 306351 (Rattus norvegicus), 720298 (Macaca mulatta)
|
| Target Alternative Names |
CERS1,CHTD6,DORV,DTGA3,Embryonic growth/differentiation factor 1,GDF-1,GDF1,Gdf-1,Gdf1,LAG1,LASS1,RAI,UOG1
|
| Uniprot Accession |
P20863,P27539
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSCAFG00845019828, ENSBTAG00000020923, ENSMUSG00000087408,ENSMUSG00000109523, ENSG00000130283, ENSMMUG00000023290
|
Pre-made viral vector of GDF1 cDNA Clones/ORF Plasmid
GDF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2657 | Pre-made Human GDF1/RAI/DORV siRNA oligo Duplex | 2657 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306351 | Pre-made Rat Gdf1 siRNA oligo Duplex | 306351 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14559 | Pre-made Mouse Gdf1/Gdf-1 siRNA oligo Duplex | 14559 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720298 | Pre-made Cynomolgus/Rhesus macaque GDF1 siRNA oligo Duplex | 720298 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096297 | Pre-made Cat/Feline GDF1 siRNA oligo Duplex | 101096297 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100686938 | Pre-made Dog/Canine GDF1 siRNA oligo Duplex | 100686938 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo104968455 | Pre-made Bovines/Cattle GDF1 siRNA oligo Duplex | 104968455 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111769683 | Pre-made Equine/Horse GDF1 siRNA oligo Duplex | 111769683 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GDF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0938-Ab | Human | Anti-Human GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-SE0938-Ab | Rat | Anti-Rat GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-SE0938-Ab | Mouse | Anti-Mouse GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0938-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0938-Ab | Cat/Feline | Anti-Cat/Feline GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-SE0938-Ab | Dog/Canine | Anti-Dog/Canine GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0938-Ab | Bovines/Cattle | Anti-Bovines/Cattle GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0938-Ab | Equine/Horse | Anti-Equine/Horse GDF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
GDF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0938-Ag | Human | Human GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0938-Ag | Rat | Rat GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0938-Ag | Mouse | Mouse GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0938-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0938-Ag | Cat/Feline | Cat/Feline GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE0938-Ag | Dog/Canine | Dog/Canine GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0938-Ag | Bovines/Cattle | Bovines/Cattle GDF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0938-Ag | Equine/Horse | Equine/Horse GDF1 recombinant protein | Mammalian cell | Detail |