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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]
| Target ID |
GM-SE0844
|
| Target Name |
LIX/CXCL5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6374
|
| Gene ID |
6374 (Homo sapiens)
|
| Target Alternative Names |
C-X-C motif chemokine 5,CXCL5,ENA-78,ENA-78(1-78),Epithelial-derived neutrophil-activating protein 78,LIX,Neutrophil-activating peptide ENA-78,SCYB5,Small-inducible cytokine B5
|
| Uniprot Accession |
P42830
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
cancer, Prostate Cancer, Malignant neoplasm of bladder
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Pertussis, Rheumatoid arthritis
|
| Gene Ensembl |
ENSG00000163735
|
Pre-made viral vector of LIX/CXCL5 cDNA Clones/ORF Plasmid
LIX/CXCL5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6374 | Pre-made Human CXCL5/SCYB5/ENA-78 siRNA oligo Duplex | 6374 | Human | In-vitro grade; in-vivo grade | Detail |
LIX/CXCL5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0844-Ab | Human | Anti-Human LIX/CXCL5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
LIX/CXCL5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0844-Ag | Human | Human LIX/CXCL5 recombinant protein | Mammalian cell | Detail |