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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]
| Target ID |
GM-SE0409
|
| Target Name |
PLA2G10
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8399
|
| Gene ID |
26565 (Mus musculus), 29359 (Rattus norvegicus), 8399 (Homo sapiens)
|
| Target Alternative Names |
GX sPLA2,GXPLA2,GXSPLA2,Group 10 secretory phospholipase A2,Group X secretory phospholipase A2 (GX sPLA2,PLA2G10,PLA2GX,Phosphatidylcholine 2-acylhydrolase 10,Pla2g10,SPLA2,sPLA2-X,sPLA2-X)
|
| Uniprot Accession |
Q9QXX3,Q9QZT3,O15496
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease from KEGG |
Metabolic pathways, Ras signaling pathway, Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism
|
| Gene Ensembl |
ENSMUSG00000022683, ENSG00000069764
|
Pre-made viral vector of PLA2G10 cDNA Clones/ORF Plasmid
PLA2G10 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8399 | Pre-made Human PLA2G10/SPLA2/GXPLA2 siRNA oligo Duplex | 8399 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29359 | Pre-made Rat Pla2g10/PLA2GX/sPLA2-X siRNA oligo Duplex | 29359 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26565 | Pre-made Mouse Pla2g10/PLA2GX/sPLA2-X siRNA oligo Duplex | 26565 | Mouse | In-vitro grade; in-vivo grade | Detail |
PLA2G10 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0409-Ab | Human | Anti-Human PLA2G10 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE0409-Ab | Rat | Anti-Rat PLA2G10 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE0409-Ab | Mouse | Anti-Mouse PLA2G10 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PLA2G10 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0409-Ag | Human | Human PLA2G10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE0409-Ag | Rat | Rat PLA2G10 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE0409-Ag | Mouse | Mouse PLA2G10 recombinant protein | Mammalian cell | Detail |
