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Target
sublocation: Transmembrane Protein.
This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP2560
|
| Target Name |
PLA2G5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5322
|
| Gene ID |
100058536 (Equus caballus), 101091796 (Felis catus), 29354 (Rattus norvegicus), 5322 (Homo sapiens) 614911 (Bos taurus), 704629 (Macaca mulatta)
|
| Target Alternative Names |
FRFB,GV-PLA2,PLA2-10,PLA2G5,Phosphatidylcholine 2-acylhydrolase 5,Phospholipase A2 group V,Pla2g5,hVPLA(2)
|
| Uniprot Accession |
P51433,P39877
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Metabolic pathways, Ras signaling pathway, Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, Linoleic acid metabolism
|
| Gene Ensembl |
ENSECAG00000006879, ENSG00000127472, ENSBTAG00000039122, ENSMMUG00000064805
|
Pre-made viral vector of PLA2G5 cDNA Clones/ORF Plasmid
PLA2G5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5322 | Pre-made Human PLA2G5/FRFB/GV-PLA2 siRNA oligo Duplex | 5322 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29354 | Pre-made Rat Pla2g5/PLA2-10 siRNA oligo Duplex | 29354 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704629 | Pre-made Cynomolgus/Rhesus macaque PLA2G5 siRNA oligo Duplex | 704629 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091796 | Pre-made Cat/Feline PLA2G5 siRNA oligo Duplex | 101091796 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614911 | Pre-made Bovines/Cattle PLA2G5 siRNA oligo Duplex | 614911 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058536 | Pre-made Equine/Horse PLA2G5 siRNA oligo Duplex | 100058536 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PLA2G5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2560-Ab | Human | Anti-Human PLA2G5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP2560-Ab | Rat | Anti-Rat PLA2G5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP2560-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PLA2G5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP2560-Ab | Cat/Feline | Anti-Cat/Feline PLA2G5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP2560-Ab | Bovines/Cattle | Anti-Bovines/Cattle PLA2G5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP2560-Ab | Equine/Horse | Anti-Equine/Horse PLA2G5 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
PLA2G5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2560-Ag | Human | Human PLA2G5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2560-Ag | Rat | Rat PLA2G5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2560-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PLA2G5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP2560-Ag | Cat/Feline | Cat/Feline PLA2G5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2560-Ag | Bovines/Cattle | Bovines/Cattle PLA2G5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2560-Ag | Equine/Horse | Equine/Horse PLA2G5 VLP (virus-like particle) | HEK293 | Products Developing |