RAB8A Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore RAB8A gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq, Jul 2008]

Target ID GM-MP2278
Target Name RAB8A
Gene Group ldentifer
(Target Gene ID in Homo species)
4218
Gene ID 100125881 (Bos taurus), 100147248 (Equus caballus), 100423251 (Macaca mulatta), 101092668 (Felis catus)
117103 (Rattus norvegicus), 17274 (Mus musculus), 403773 (Canis lupus familiaris), 4218 (Homo sapiens)
Target Alternative Names MEL,Mel,Oncogene c-mel,RAB8,RAB8A,Rab8,Rab8a,Ras-related protein Rab-8A
Uniprot Accession A4FV54,P35280,P55258,P61007,P61006
Protein Sub-location Transmembrane Protein
Disease cancer
Disease from KEGG Tight junction, Pancreatic secretion
Gene Ensembl ENSBTAG00000038696, ENSECAG00000053880, ENSMMUG00000056960, ENSMUSG00000003037, ENSCAFG00845030471, ENSG00000167461
Target Classification Tumor-associated antigen (TAA)


Pre-made viral vector of RAB8A cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP004586Human Rab8a/MEL/RAB8 Lentivirus plasmidNM_0053704218HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001767Human RAB8A/MEL/RAB8 Lentivirus plasmidNM_0053704218HumanLentivirus plasmidnull3xflag (C-Terminal)CMVDetail
vGMLP004586Human Rab8a/MEL/RAB8 Lentivirus particleNM_0053704218HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001767Human RAB8A/MEL/RAB8 Lentivirus particleNM_0053704218HumanLentivirus particlenull3xflag (C-Terminal)CMVDetail
pGMAAV000990Mouse Rab8a/AA409338/Mel Adeno-associate virus(AAV) plasmidNM_023126.217274MouseAdeno-associate virus(AAV) plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm003717Mouse Rab8a/AA409338/Mel Lentivirus plasmidNM_023126.217274MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC000550Mouse Rab8a/AA409338/Me Mammalian (Non-Viral Vector) plasmidNM_023126.217274MouseMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMAAV000990Mouse Rab8a/AA409338/Mel Adeno-associate virus(AAV) particleNM_023126.217274MouseAdeno-associate virus(AAV) particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm003717Mouse Rab8a/AA409338/Mel Lentivirus particleNM_023126.217274MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


RAB8A siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo4218Pre-made Human RAB8A/MEL/RAB8 siRNA oligo Duplex4218HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo117103Pre-made Rat Rab8a/Mel/Rab8 siRNA oligo Duplex117103RatIn-vitro grade; in-vivo gradeDetail
pGMoligo17274Pre-made Mouse Rab8a/Mel siRNA oligo Duplex17274MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo100423251Pre-made Cynomolgus/Rhesus macaque RAB8A siRNA oligo Duplex100423251Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092668Pre-made Cat/Feline RAB8A siRNA oligo Duplex101092668Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo403773Pre-made Dog/Canine RAB8A/RAB8 siRNA oligo Duplex403773Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo100125881Pre-made Bovines/Cattle RAB8A siRNA oligo Duplex100125881Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100147248Pre-made Equine/Horse RAB8A siRNA oligo Duplex100147248Equine/HorseIn-vitro grade; in-vivo gradeDetail


RAB8A antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-MP2278-AbHumanAnti-Human RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-rg-MP2278-AbRatAnti-Rat RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-mg-MP2278-AbMouseAnti-Mouse RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cynog-MP2278-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-felg-MP2278-AbCat/FelineAnti-Cat/Feline RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-cang-MP2278-AbDog/CanineAnti-Dog/Canine RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-bovg-MP2278-AbBovines/CattleAnti-Bovines/Cattle RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail
GM-Tg-equg-MP2278-AbEquine/HorseAnti-Equine/Horse RAB8A monoclonal antibodymabFACS/Biofunctional AntibodyDetail


RAB8A VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-MP2278-AgHumanHuman RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-MP2278-AgRatRat RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-MP2278-AgMouseMouse RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-MP2278-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-MP2278-AgCat/FelineCat/Feline RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-MP2278-AgDog/CanineDog/Canine RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-MP2278-AgBovines/CattleBovines/Cattle RAB8A VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-MP2278-AgEquine/HorseEquine/Horse RAB8A VLP (virus-like particle)HEK293Products Developing