Explore SCN1B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
| Target ID |
GM-MP1487
|
| Target Name |
SCN1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6324
|
| Gene ID |
100050415 (Equus caballus), 101101526 (Felis catus), 20266 (Mus musculus), 29686 (Rattus norvegicus)
484584 (Canis lupus familiaris), 618204 (Bos taurus), 6324 (Homo sapiens), 707134 (Macaca mulatta)
|
| Target Alternative Names |
ATFB13,BRGDA5,DEE52,EIEE52,GEFSP1,SCN1B,Scn1b,Sodium channel regulatory subunit beta-1
|
| Uniprot Accession |
P97952,Q00954,Q4PPC4,Q17QN4,Q07699
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
Adrenergic signaling in cardiomyocytes
|
| Gene Ensembl |
ENSECAG00000000179, ENSMUSG00000019194, ENSCAFG00845003824, ENSBTAG00000003826, ENSG00000105711, ENSMMUG00000004843
|
Pre-made viral vector of SCN1B cDNA Clones/ORF Plasmid
SCN1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6324 | Pre-made Human SCN1B/DEE52/ATFB13 siRNA oligo Duplex | 6324 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29686 | Pre-made Rat Scn1b siRNA oligo Duplex | 29686 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20266 | Pre-made Mouse Scn1b siRNA oligo Duplex | 20266 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707134 | Pre-made Cynomolgus/Rhesus macaque SCN1B siRNA oligo Duplex | 707134 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101526 | Pre-made Cat/Feline SCN1B siRNA oligo Duplex | 101101526 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484584 | Pre-made Dog/Canine SCN1B siRNA oligo Duplex | 484584 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo618204 | Pre-made Bovines/Cattle SCN1B siRNA oligo Duplex | 618204 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050415 | Pre-made Equine/Horse SCN1B siRNA oligo Duplex | 100050415 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SCN1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP1487-Ab | Human | Anti-Human SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP1487-Ab | Rat | Anti-Rat SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP1487-Ab | Mouse | Anti-Mouse SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP1487-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP1487-Ab | Cat/Feline | Anti-Cat/Feline SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP1487-Ab | Dog/Canine | Anti-Dog/Canine SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP1487-Ab | Bovines/Cattle | Anti-Bovines/Cattle SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP1487-Ab | Equine/Horse | Anti-Equine/Horse SCN1B monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
SCN1B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP1487-Ag | Human | Human SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP1487-Ag | Rat | Rat SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP1487-Ag | Mouse | Mouse SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP1487-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP1487-Ag | Cat/Feline | Cat/Feline SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP1487-Ag | Dog/Canine | Dog/Canine SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP1487-Ag | Bovines/Cattle | Bovines/Cattle SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP1487-Ag | Equine/Horse | Equine/Horse SCN1B VLP (virus-like particle) | HEK293 | Products Developing |
