GYPB/CD235b Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

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Target sublocation: Transmembrane Protein.
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Target ID	GM-MP0566
Target Name	GYPB/CD235b
Gene Group ldentifer （Target Gene ID in Homo species)	2994
Gene ID	2994 (Homo sapiens)
Target Alternative Names	CD235b,GPB,GYP,GYPA,GYPB,Glycophorin-B,MNS,PAS-3,SS,SS-active sialoglycoprotein,Sialoglycoprotein delta
Uniprot Accession	P06028
Protein Sub-location	Transmembrane Protein
Disease from KEGG	Malaria
Gene Ensembl	ENSG00000250361

Pre-made viral vector of GYPB/CD235b cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP002304	Human GYPB/CD235b/GPB Lentivirus plasmid	NM_002100	2994	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP002304	Human GYPB/CD235b/GPB Lentivirus particle	NM_002100	2994	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

GYPB/CD235b siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo2994	Pre-made Human GYPB/SS/GPB siRNA oligo Duplex	2994	Human	In-vitro grade; in-vivo grade	Detail

GYPB/CD235b antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-MP0566-Ab	Human	Anti-Human GYPB/CD235b monoclonal antibody	mab	FACS/Biofunctional Antibody	Detail

GYPB/CD235b VLP (virus-like particle)/protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-MP0566-Ag	Human	Human GYPB/CD235b VLP (virus-like particle)	HEK293	Products Developing