Explore EFNA1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0392
|
| Target Name |
EFNA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1942
|
| Gene ID |
100063307 (Equus caballus), 101094570 (Felis catus), 13636 (Mus musculus), 1942 (Homo sapiens)
490431 (Canis lupus familiaris), 507319 (Bos taurus), 717399 (Macaca mulatta), 94268 (Rattus norvegicus)
|
| Target Alternative Names |
B61,ECKLG,EFL1,EFNA1,EPH-related receptor tyrosine kinase ligand 1 (LERK-1),EPLG1,Efl1,Efna1,Ephrin-A1,Epl1,Eplg1,GMAN,Immediate early response protein B61,LERK-1,LERK1,Lerk1,TNFAIP4,Tumor necrosis factor alpha-induced protein 4 (TNF alpha-induced protein 4)
|
| Uniprot Accession |
P52793,P20827,Q3ZC64,P97553
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, PI3K-Akt signaling pathway, Axon guidance
|
| Gene Ensembl |
ENSMUSG00000027954, ENSG00000169242, ENSCAFG00845013438, ENSBTAG00000020244, ENSMMUG00000005350
|
Pre-made viral vector of EFNA1 cDNA Clones/ORF Plasmid
EFNA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1942 | Pre-made Human EFNA1/B61/EFL1 siRNA oligo Duplex | 1942 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo94268 | Pre-made Rat Efna1/B61 siRNA oligo Duplex | 94268 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13636 | Pre-made Mouse Efna1/B61/Efl1 siRNA oligo Duplex | 13636 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717399 | Pre-made Cynomolgus/Rhesus macaque EFNA1 siRNA oligo Duplex | 717399 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094570 | Pre-made Cat/Feline EFNA1 siRNA oligo Duplex | 101094570 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490431 | Pre-made Dog/Canine EFNA1 siRNA oligo Duplex | 490431 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507319 | Pre-made Bovines/Cattle EFNA1 siRNA oligo Duplex | 507319 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063307 | Pre-made Equine/Horse EFNA1 siRNA oligo Duplex | 100063307 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EFNA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0392-Ab | Human | Anti-Human EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0392-Ab | Rat | Anti-Rat EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0392-Ab | Mouse | Anti-Mouse EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0392-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0392-Ab | Cat/Feline | Anti-Cat/Feline EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0392-Ab | Dog/Canine | Anti-Dog/Canine EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0392-Ab | Bovines/Cattle | Anti-Bovines/Cattle EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0392-Ab | Equine/Horse | Anti-Equine/Horse EFNA1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
EFNA1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0392-Ag | Human | Human EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0392-Ag | Rat | Rat EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0392-Ag | Mouse | Mouse EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0392-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0392-Ag | Cat/Feline | Cat/Feline EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0392-Ag | Dog/Canine | Dog/Canine EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0392-Ag | Bovines/Cattle | Bovines/Cattle EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0392-Ag | Equine/Horse | Equine/Horse EFNA1 VLP (virus-like particle) | HEK293 | Products Developing |
