Explore CYBA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0344
|
| Target Name |
CYBA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1535
|
| Gene ID |
100049843 (Equus caballus), 101091745 (Felis catus), 13057 (Mus musculus), 1535 (Homo sapiens)
281111 (Bos taurus), 489664 (Canis lupus familiaris), 696748 (Macaca mulatta), 79129 (Rattus norvegicus)
|
| Target Alternative Names |
CGD4,CYBA,Cyba,Cytochrome b(558) alpha chain,Cytochrome b-245 light chain,Cytochrome b558 subunit alpha,Neutrophil cytochrome b 22 kDa polypeptide,Phox,Superoxide-generating NADPH oxidase light chain subunit,b558,nmf333,p22 phagocyte B-cytochrome,p22-PHOX,p22-phox,p22-phox (p22phox),p22phox
|
| Uniprot Accession |
Q61462,P13498,O46521,Q62737
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Phagosome, Osteoclast differentiation, NOD-like receptor signaling pathway, Leukocyte transendothelial migration, Leishmaniasis, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSMUSG00000006519, ENSG00000051523, ENSBTAG00000061619, ENSCAFG00845003520, ENSMMUG00000053929
|
Pre-made viral vector of CYBA cDNA Clones/ORF Plasmid
CYBA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1535 | Pre-made Human CYBA/CGD4/p22-PHOX siRNA oligo Duplex | 1535 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo79129 | Pre-made Rat Cyba/Phox/p22-phox siRNA oligo Duplex | 79129 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13057 | Pre-made Mouse Cyba/b558/nmf333 siRNA oligo Duplex | 13057 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696748 | Pre-made Cynomolgus/Rhesus macaque CYBA siRNA oligo Duplex | 696748 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091745 | Pre-made Cat/Feline CYBA siRNA oligo Duplex | 101091745 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489664 | Pre-made Dog/Canine CYBA siRNA oligo Duplex | 489664 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281111 | Pre-made Bovines/Cattle CYBA siRNA oligo Duplex | 281111 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100049843 | Pre-made Equine/Horse CYBA siRNA oligo Duplex | 100049843 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CYBA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0344-Ab | Human | Anti-Human CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0344-Ab | Rat | Anti-Rat CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0344-Ab | Mouse | Anti-Mouse CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0344-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0344-Ab | Cat/Feline | Anti-Cat/Feline CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0344-Ab | Dog/Canine | Anti-Dog/Canine CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0344-Ab | Bovines/Cattle | Anti-Bovines/Cattle CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0344-Ab | Equine/Horse | Anti-Equine/Horse CYBA monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CYBA VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0344-Ag | Human | Human CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0344-Ag | Rat | Rat CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0344-Ag | Mouse | Mouse CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0344-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0344-Ag | Cat/Feline | Cat/Feline CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0344-Ag | Dog/Canine | Dog/Canine CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0344-Ag | Bovines/Cattle | Bovines/Cattle CYBA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0344-Ag | Equine/Horse | Equine/Horse CYBA VLP (virus-like particle) | HEK293 | Products Developing |
