Explore Claudin 7/CLDN7 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
Target ID |
GM-MP0286
|
Target Name |
Claudin 7/CLDN7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1366
|
Gene ID |
100072960 (Equus caballus), 101096019 (Felis catus), 1366 (Homo sapiens), 489466 (Canis lupus familiaris) 512975 (Bos taurus), 53624 (Mus musculus), 65132 (Rattus norvegicus), 714647 (Macaca mulatta)
|
Target Alternative Names |
CLDN7,Cldn7,CLDN-7,CEPTRL2,CPETRL2,Hs.84359,claudin-1,cld-7
|
Uniprot Accession |
O95471,Q3B7N4,Q9Z261,Q9Z1L1
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
|
Disease |
cancer
|
Disease from KEGG |
Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Hepatitis C
|
Gene Ensembl |
ENSECAG00000007289, ENSG00000181885, ENSCAFG00845020640, ENSBTAG00000019448, ENSMUSG00000018569, ENSMMUG00000010551
|
Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Claudin 7/CLDN7 cDNA Clones/ORF Plasmid
Claudin 7/CLDN7 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo1366 | Pre-made Human CLDN7/CLDN-7/CEPTRL2 siRNA oligo Duplex | 1366 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo65132 | Pre-made Rat Cldn7/cld-7 siRNA oligo Duplex | 65132 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo53624 | Pre-made Mouse Cldn7 siRNA oligo Duplex | 53624 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo714647 | Pre-made Cynomolgus/Rhesus macaque CLDN7 siRNA oligo Duplex | 714647 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101096019 | Pre-made Cat/Feline CLDN7 siRNA oligo Duplex | 101096019 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo489466 | Pre-made Dog/Canine CLDN7 siRNA oligo Duplex | 489466 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo512975 | Pre-made Bovines/Cattle CLDN7 siRNA oligo Duplex | 512975 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100072960 | Pre-made Equine/Horse CLDN7 siRNA oligo Duplex | 100072960 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Claudin 7/CLDN7 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-MP0286-Ab | Human | Anti-Human Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-rg-MP0286-Ab | Rat | Anti-Rat Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-mg-MP0286-Ab | Mouse | Anti-Mouse Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cynog-MP0286-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-felg-MP0286-Ab | Cat/Feline | Anti-Cat/Feline Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-cang-MP0286-Ab | Dog/Canine | Anti-Dog/Canine Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-bovg-MP0286-Ab | Bovines/Cattle | Anti-Bovines/Cattle Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
GM-Tg-equg-MP0286-Ab | Equine/Horse | Anti-Equine/Horse Claudin 7/CLDN7 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Claudin 7/CLDN7 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-MP0286-Ag | Human | Human Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-MP0286-Ag | Rat | Rat Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-MP0286-Ag | Mouse | Mouse Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-MP0286-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-MP0286-Ag | Cat/Feline | Cat/Feline Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-MP0286-Ag | Dog/Canine | Dog/Canine Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-MP0286-Ag | Bovines/Cattle | Bovines/Cattle Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-MP0286-Ag | Equine/Horse | Equine/Horse Claudin 7/CLDN7 VLP (virus-like particle) | HEK293 | Products Developing |