Explore CD81 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
| Target ID |
GM-MP0217
|
| Target Name |
CD81
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
975
|
| Gene ID |
100060480 (Equus caballus), 101093144 (Felis catus), 12520 (Mus musculus), 25621 (Rattus norvegicus) 511435 (Bos taurus), 611606 (Canis lupus familiaris), 704961 (Macaca mulatta), 975 (Homo sapiens)
|
| Target Alternative Names |
26 kDa cell surface protein TAPA-1,CD81,CD81 antigen,CVID6,Cd81,S5.7,TAPA1,TSPAN28,Tapa-1,Tapa1,Target of the antiproliferative antibody 1,Tetraspanin-28 (Tspan-28),Tspan28
|
| Uniprot Accession |
P35762,Q62745,Q3ZCD0,P60033
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
B cell receptor signaling pathway, Malaria, Hepatitis C
|
| Gene Ensembl |
ENSECAG00000024654, ENSMUSG00000037706, ENSCAFG00845010894, ENSMMUG00000002043, ENSG00000110651
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD81 cDNA Clones/ORF Plasmid
CD81 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo975 | Pre-made Human CD81/S5.7/CVID6 siRNA oligo Duplex | 975 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25621 | Pre-made Rat Cd81/Tapa1 siRNA oligo Duplex | 25621 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12520 | Pre-made Mouse Cd81/Tapa1/Tapa-1 siRNA oligo Duplex | 12520 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704961 | Pre-made Cynomolgus/Rhesus macaque CD81 siRNA oligo Duplex | 704961 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093144 | Pre-made Cat/Feline CD81 siRNA oligo Duplex | 101093144 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611606 | Pre-made Dog/Canine CD81 siRNA oligo Duplex | 611606 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511435 | Pre-made Bovines/Cattle CD81 siRNA oligo Duplex | 511435 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060480 | Pre-made Equine/Horse CD81 siRNA oligo Duplex | 100060480 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD81 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0217-Ab | Human | Anti-Human CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0217-Ab | Rat | Anti-Rat CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0217-Ab | Mouse | Anti-Mouse CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0217-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0217-Ab | Cat/Feline | Anti-Cat/Feline CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0217-Ab | Dog/Canine | Anti-Dog/Canine CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0217-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0217-Ab | Equine/Horse | Anti-Equine/Horse CD81 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD81 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0217-Ag | Human | Human CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0217-Ag | Rat | Rat CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0217-Ag | Mouse | Mouse CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0217-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0217-Ag | Cat/Feline | Cat/Feline CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0217-Ag | Dog/Canine | Dog/Canine CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0217-Ag | Bovines/Cattle | Bovines/Cattle CD81 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0217-Ag | Equine/Horse | Equine/Horse CD81 VLP (virus-like particle) | HEK293 | Products Developing |