Explore CD48 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
| Target ID |
GM-MP0212
|
| Target Name |
CD48
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
962
|
| Gene ID |
100053868 (Equus caballus), 101089831 (Felis catus), 12506 (Mus musculus), 245962 (Rattus norvegicus)
488642 (Canis lupus familiaris), 508386 (Bos taurus), 719762 (Macaca mulatta), 962 (Homo sapiens)
|
| Target Alternative Names |
B-lymphocyte activation marker BLAST-1,BCM1,BCM1 surface antigen,BLAST,BLAST-1,BLAST1,Bcm-1,CD48,CD48 antigen,Cd48,Leukocyte antigen MEM-102,MEM-102,SLAM family member 2 (SLAMF2),SLAMF2,Sgp-60,Signaling lymphocytic activation molecule 2,TCT.1,hCD48,mCD48
|
| Uniprot Accession |
P18181,P10252,P09326
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity
|
| Gene Ensembl |
ENSECAG00000013345, ENSMUSG00000015355, ENSCAFG00845030234, ENSBTAG00000011238, ENSMMUG00000015812, ENSG00000117091
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD48 cDNA Clones/ORF Plasmid
CD48 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo962 | Pre-made Human CD48/BCM1/BLAST siRNA oligo Duplex | 962 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo245962 | Pre-made Rat Cd48/SLAMF2 siRNA oligo Duplex | 245962 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12506 | Pre-made Mouse Cd48/BCM1/BLAST siRNA oligo Duplex | 12506 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719762 | Pre-made Cynomolgus/Rhesus macaque CD48 siRNA oligo Duplex | 719762 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089831 | Pre-made Cat/Feline CD48 siRNA oligo Duplex | 101089831 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488642 | Pre-made Dog/Canine CD48 siRNA oligo Duplex | 488642 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508386 | Pre-made Bovines/Cattle CD48 siRNA oligo Duplex | 508386 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053868 | Pre-made Equine/Horse CD48 siRNA oligo Duplex | 100053868 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD48 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0212-Ab | Human | Anti-Human CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0212-Ab | Rat | Anti-Rat CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0212-Ab | Mouse | Anti-Mouse CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0212-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0212-Ab | Cat/Feline | Anti-Cat/Feline CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0212-Ab | Dog/Canine | Anti-Dog/Canine CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0212-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0212-Ab | Equine/Horse | Anti-Equine/Horse CD48 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD48 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0212-Ag | Human | Human CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0212-Ag | Rat | Rat CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0212-Ag | Mouse | Mouse CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0212-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0212-Ag | Cat/Feline | Cat/Feline CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0212-Ag | Dog/Canine | Dog/Canine CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0212-Ag | Bovines/Cattle | Bovines/Cattle CD48 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0212-Ag | Equine/Horse | Equine/Horse CD48 VLP (virus-like particle) | HEK293 | Products Developing |
