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Target
sublocation: Transmembrane Protein.
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
| Target ID |
GM-MP0200
|
| Target Name |
CD1d/CD1D
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
912
|
| Gene ID |
101100784 (Felis catus), 12479 (Mus musculus), 613268 (Macaca mulatta), 912 (Homo sapiens)
|
| Target Alternative Names |
Antigen-presenting glycoprotein CD1d,CD1.1,CD1A,CD1D,CD1d,Cd1a,Cd1d,Cd1d1,Ly-38,R3,R3G1
|
| Uniprot Accession |
P11609,P15813
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Tight junction, Hematopoietic cell lineage, Amoebiasis
|
| Gene Ensembl |
ENSMUSG00000028076, ENSMMUG00000020156, ENSG00000158473
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CD1d/CD1D cDNA Clones/ORF Plasmid
CD1d/CD1D siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo912 | Pre-made Human CD1D/R3/CD1A siRNA oligo Duplex | 912 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12479 | Pre-made Mouse Cd1d1/Cd1a/Cd1d siRNA oligo Duplex | 12479 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613268 | Pre-made Cynomolgus/Rhesus macaque CD1D siRNA oligo Duplex | 613268 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100784 | Pre-made Cat/Feline CD1D siRNA oligo Duplex | 101100784 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
CD1d/CD1D antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0200-Ab | Human | Anti-Human CD1d/CD1D monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0200-Ab | Mouse | Anti-Mouse CD1d/CD1D monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0200-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD1d/CD1D monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0200-Ab | Cat/Feline | Anti-Cat/Feline CD1d/CD1D monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD1d/CD1D VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0200-Ag | Human | Human CD1d/CD1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0200-Ag | Mouse | Mouse CD1d/CD1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0200-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD1d/CD1D VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0200-Ag | Cat/Feline | Cat/Feline CD1d/CD1D VLP (virus-like particle) | HEK293 | Products Developing |
