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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010]
| Target ID |
GM-IP9753
|
| Target Name |
MAGEL2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
54551
|
| Gene ID |
100060915 (Equus caballus), 100684492 (Canis lupus familiaris), 101088670 (Felis catus), 27385 (Mus musculus)
538665 (Bos taurus), 54551 (Homo sapiens), 679875 (Rattus norvegicus), 719760 (Macaca mulatta)
|
| Target Alternative Names |
MAGE-like protein 2,MAGEL2,Mage-l2,Magel2,NDNL1,Necdin-like protein 1,PWLS,Protein nM15,SHFYNG,nM15,ns7
|
| Uniprot Accession |
Q9QZ04,Q9UJ55
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000013555, ENSCAFG00845019742, ENSMUSG00000056972, ENSBTAG00000045998, ENSG00000254585
|
MAGEL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo54551 | Pre-made Human MAGEL2/PWLS/nM15 siRNA oligo Duplex | 54551 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo679875 | Pre-made Rat Magel2 siRNA oligo Duplex | 679875 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo27385 | Pre-made Mouse Magel2/ns7/nM15 siRNA oligo Duplex | 27385 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719760 | Pre-made Cynomolgus/Rhesus macaque MAGEL2 siRNA oligo Duplex | 719760 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088670 | Pre-made Cat/Feline MAGEL2 siRNA oligo Duplex | 101088670 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100684492 | Pre-made Dog/Canine MAGEL2 siRNA oligo Duplex | 100684492 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538665 | Pre-made Bovines/Cattle MAGEL2 siRNA oligo Duplex | 538665 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060915 | Pre-made Equine/Horse MAGEL2 siRNA oligo Duplex | 100060915 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAGEL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP9753-Ab | Human | Anti-Human MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP9753-Ab | Rat | Anti-Rat MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP9753-Ab | Mouse | Anti-Mouse MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP9753-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP9753-Ab | Cat/Feline | Anti-Cat/Feline MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP9753-Ab | Dog/Canine | Anti-Dog/Canine MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP9753-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAGEL2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP9753-Ab | Equine/Horse | Anti-Equine/Horse MAGEL2 monoclonal antibody | mab | | Detail |
MAGEL2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP9753-Ag | Human | Human MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP9753-Ag | Rat | Rat MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP9753-Ag | Mouse | Mouse MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP9753-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP9753-Ag | Cat/Feline | Cat/Feline MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP9753-Ag | Dog/Canine | Dog/Canine MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP9753-Ag | Bovines/Cattle | Bovines/Cattle MAGEL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP9753-Ag | Equine/Horse | Equine/Horse MAGEL2 recombinant protein | Mammalian cell | Detail |
