Explore ARNT/HIF-1 beta/HIF1B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
| Target ID |
GM-IP8766
|
| Target Name |
ARNT/HIF-1 beta/HIF1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
405
|
| Gene ID |
100059178 (Equus caballus), 101093627 (Felis catus), 11863 (Mus musculus), 119863992 (Canis lupus familiaris)
25242 (Rattus norvegicus), 281010 (Bos taurus), 405 (Homo sapiens), 715971 (Macaca mulatta)
|
| Target Alternative Names |
ARNT,ARNT protein,ARNT1,Arnt,Arnt1,Aryl hydrocarbon receptor nuclear translocator,Class E basic helix-loop-helix protein 2 (bHLHe2),D3Ertd557e,Dioxin receptor,Drnt,ESTM42,HIF-1 beta,HIF-1-beta,HIF-1beta,HIF1-beta,HIF1-beta),HIF1B,HIF1BETA,Hif1b,Hypoxia-inducible factor 1-beta (HIF-1-beta,TANGO,bHLHe2,mKIAA4051,nuclear translocator
|
| Uniprot Accession |
P53762,P41739,Q9BE97,P27540
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000009602, ENSMUSG00000015522, ENSCAFG00845019671, ENSBTAG00000021037, ENSG00000143437, ENSMMUG00000000541
|
Pre-made viral vector of ARNT/HIF-1 beta/HIF1B cDNA Clones/ORF Plasmid
ARNT/HIF-1 beta/HIF1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo405 | Pre-made Human ARNT/ARNT1/HIF1B siRNA oligo Duplex | 405 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25242 | Pre-made Rat Arnt/Arnt1 siRNA oligo Duplex | 25242 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11863 | Pre-made Mouse Arnt/Drnt/Hif1b siRNA oligo Duplex | 11863 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715971 | Pre-made Cynomolgus/Rhesus macaque ARNT siRNA oligo Duplex | 715971 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093627 | Pre-made Cat/Feline ARNT siRNA oligo Duplex | 101093627 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119863992 | Pre-made Dog/Canine ARNT/ARNT1 siRNA oligo Duplex | 119863992 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281010 | Pre-made Bovines/Cattle ARNT siRNA oligo Duplex | 281010 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059178 | Pre-made Equine/Horse ARNT siRNA oligo Duplex | 100059178 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ARNT/HIF-1 beta/HIF1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8766-Ab | Human | Anti-Human ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8766-Ab | Rat | Anti-Rat ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8766-Ab | Mouse | Anti-Mouse ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8766-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8766-Ab | Cat/Feline | Anti-Cat/Feline ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8766-Ab | Dog/Canine | Anti-Dog/Canine ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8766-Ab | Bovines/Cattle | Anti-Bovines/Cattle ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8766-Ab | Equine/Horse | Anti-Equine/Horse ARNT/HIF-1 beta/HIF1B monoclonal antibody | mab | | Detail |
ARNT/HIF-1 beta/HIF1B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8766-Ag | Human | Human ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8766-Ag | Rat | Rat ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8766-Ag | Mouse | Mouse ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8766-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8766-Ag | Cat/Feline | Cat/Feline ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8766-Ag | Dog/Canine | Dog/Canine ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8766-Ag | Bovines/Cattle | Bovines/Cattle ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8766-Ag | Equine/Horse | Equine/Horse ARNT/HIF-1 beta/HIF1B recombinant protein | Mammalian cell | Detail |
