Explore PHOX2A gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP8715
|
| Target Name |
PHOX2A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
401
|
| Gene ID |
100052674 (Equus caballus), 101095370 (Felis catus), 116648 (Rattus norvegicus), 11859 (Mus musculus)
401 (Homo sapiens), 485208 (Canis lupus familiaris), 507670 (Bos taurus), 718436 (Macaca mulatta)
|
| Target Alternative Names |
ARIX,ARIX1 homeodomain protein,Aristaless homeobox protein homolog,Arix,CFEOM2,FEOM2,NCAM2,PHOX2A,PMX2A,Paired mesoderm homeobox protein 2A,Paired-like homeobox 2A,Phox2,Phox2a,Pmx2,Pmx2a,Px2a
|
| Uniprot Accession |
Q62782,Q62066,O14813
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000016514, ENSMUSG00000007946, ENSG00000165462, ENSCAFG00845010206, ENSBTAG00000019168, ENSMMUG00000060629
|
Pre-made viral vector of PHOX2A cDNA Clones/ORF Plasmid
PHOX2A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo401 | Pre-made Human PHOX2A/ARIX/FEOM2 siRNA oligo Duplex | 401 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116648 | Pre-made Rat Phox2a/Arix siRNA oligo Duplex | 116648 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11859 | Pre-made Mouse Phox2a/Arix/Pmx2 siRNA oligo Duplex | 11859 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718436 | Pre-made Cynomolgus/Rhesus macaque PHOX2A siRNA oligo Duplex | 718436 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095370 | Pre-made Cat/Feline PHOX2A siRNA oligo Duplex | 101095370 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485208 | Pre-made Dog/Canine PHOX2A siRNA oligo Duplex | 485208 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507670 | Pre-made Bovines/Cattle PHOX2A siRNA oligo Duplex | 507670 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052674 | Pre-made Equine/Horse PHOX2A siRNA oligo Duplex | 100052674 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PHOX2A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8715-Ab | Human | Anti-Human PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP8715-Ab | Rat | Anti-Rat PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP8715-Ab | Mouse | Anti-Mouse PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP8715-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP8715-Ab | Cat/Feline | Anti-Cat/Feline PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP8715-Ab | Dog/Canine | Anti-Dog/Canine PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP8715-Ab | Bovines/Cattle | Anti-Bovines/Cattle PHOX2A monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP8715-Ab | Equine/Horse | Anti-Equine/Horse PHOX2A monoclonal antibody | mab | | Detail |
PHOX2A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8715-Ag | Human | Human PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP8715-Ag | Rat | Rat PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP8715-Ag | Mouse | Mouse PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP8715-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP8715-Ag | Cat/Feline | Cat/Feline PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP8715-Ag | Dog/Canine | Dog/Canine PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP8715-Ag | Bovines/Cattle | Bovines/Cattle PHOX2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP8715-Ag | Equine/Horse | Equine/Horse PHOX2A recombinant protein | Mammalian cell | Detail |
