ARHGDIB Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

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Target sublocation: Introcelluar Protein.
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]

Pre-made viral vector of ARHGDIB cDNA Clones/ORF Plasmid

ARHGDIB siRNA/miRNA/oligo for RNA interfence (RNAi)

ARHGDIB antibody/GMab

ARHGDIB recombinant protein