Explore Keratin 81/KRT81 gene products and cross-species
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. Some human genome assemblies (example T2T-CHM13) have a non-coding version of the gene due to the presence of a SNP that introduces a premature stop codon after codon 281. [provided by RefSeq, Jan 2024]
| Target ID |
GM-IP8522
|
| Target Name |
Keratin 81/KRT81
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3887
|
| Gene ID |
3887 (Homo sapiens)
|
| Target Alternative Names |
1,HB1,Hair keratin K2.9,Hb-1,K81,KRT81,KRTHB1,Keratin,Keratin 81,Keratin-81 (K81),MLN137,Metastatic lymph node 137 gene protein (MLN 137),Type II hair keratin Hb1,Type-II keratin Kb21,basic,ghHKb1 (ghHb1),ghHkb1,hHAKB2-1,hair,type II cuticular Hb1
|
| Uniprot Accession |
Q14533
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSG00000205426
|
Keratin 81/KRT81 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3887 | Pre-made Human KRT81/HB1/K81 siRNA oligo Duplex | 3887 | Human | In-vitro grade; in-vivo grade | Detail |
Keratin 81/KRT81 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP8522-Ab | Human | Anti-Human Keratin 81/KRT81 monoclonal antibody | mab | | Detail |
Keratin 81/KRT81 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP8522-Ag | Human | Human Keratin 81/KRT81 recombinant protein | Mammalian cell | Detail |
